BRD-K05151076_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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47 genes differentially expressed following the BRD-K05151076_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALCAM activated leukocyte cell adhesion molecule
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CAST calpastatin
CD9 CD9 molecule
CLIC4 chloride intracellular channel 4
CLU clusterin
CXCL13 chemokine (C-X-C motif) ligand 13
DDIT4 DNA-damage-inducible transcript 4
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GSTM3 glutathione S-transferase mu 3 (brain)
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP11 glucuronidase, beta pseudogene 11
ILK integrin-linked kinase
JCHAIN joining chain of multimeric IgA and IgM
MAP7 microtubule-associated protein 7
MT1F metallothionein 1F
MYO6 myosin VI
NNMT nicotinamide N-methyltransferase
NRCAM neuronal cell adhesion molecule
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
STK39 serine threonine kinase 39
TIMP2 TIMP metallopeptidase inhibitor 2
TRIB3 tribbles pseudokinase 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
CCND1 cyclin D1
FHL2 four and a half LIM domains 2
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
IER3 immediate early response 3
KCTD12 potassium channel tetramerization domain containing 12
KLK11 kallikrein-related peptidase 11
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PPIF peptidylprolyl isomerase F
PRSS23 protease, serine, 23
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPDEF SAM pointed domain containing ETS transcription factor
TBC1D31 TBC1 domain family, member 31
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
WT1 Wilms tumor 1