Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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118 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ADRB2 | adrenoceptor beta 2, surface |
APOC1 | apolipoprotein C-I |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
BAG3 | BCL2-associated athanogene 3 |
CD52 | CD52 molecule |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHIC2 | cysteine-rich hydrophobic domain 2 |
CLDN3 | claudin 3 |
CLU | clusterin |
COL11A1 | collagen, type XI, alpha 1 |
COL1A1 | collagen, type I, alpha 1 |
CTSZ | cathepsin Z |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EIF5A | eukaryotic translation initiation factor 5A |
FAS | Fas cell surface death receptor |
FTH1 | ferritin, heavy polypeptide 1 |
FXYD6 | FXYD domain containing ion transport regulator 6 |
GCLC | glutamate-cysteine ligase, catalytic subunit |
GCLM | glutamate-cysteine ligase, modifier subunit |
HIST1H2BG | histone cluster 1, H2bg |
HMOX1 | heme oxygenase 1 |
HPSE | heparanase |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IL7R | interleukin 7 receptor |
JUN | jun proto-oncogene |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
KDM6B | lysine (K)-specific demethylase 6B |
LBH | limb bud and heart development |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MMP1 | matrix metallopeptidase 1 |
MT1M | metallothionein 1M |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PEG3 | paternally expressed 3 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PSAP | prosaposin |
PTN | pleiotrophin |
S100A8 | S100 calcium binding protein A8 |
SCG5 | secretogranin V |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SPON1 | spondin 1, extracellular matrix protein |
SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
SRGN | serglycin |
TMEM176B | transmembrane protein 176B |
TXNIP | thioredoxin interacting protein |
TXNRD1 | thioredoxin reductase 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
ZFP36 | ZFP36 ring finger protein |
Symbol | Name |
---|---|
A2M | alpha-2-macroglobulin |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
AURKB | aurora kinase B |
BTBD3 | BTB (POZ) domain containing 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CCNB1 | cyclin B1 |
CCND1 | cyclin D1 |
CD59 | CD59 molecule, complement regulatory protein |
CDC20 | cell division cycle 20 |
CDC25B | cell division cycle 25B |
CHGB | chromogranin B |
CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
DLD | dihydrolipoamide dehydrogenase |
EDNRB | endothelin receptor type B |
ERBB3 | erb-b2 receptor tyrosine kinase 3 |
FABP4 | fatty acid binding protein 4, adipocyte |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FAM3C | family with sequence similarity 3, member C |
GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HOXA5 | homeobox A5 |
IER3 | immediate early response 3 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP3 | insulin-like growth factor binding protein 3 |
ISG15 | ISG15 ubiquitin-like modifier |
ITGA6 | integrin, alpha 6 |
JADE2 | jade family PHD finger 2 |
KIF20A | kinesin family member 20A |
KIF2C | kinesin family member 2C |
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
LAMB1 | laminin, beta 1 |
LRRC17 | leucine rich repeat containing 17 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MCAM | melanoma cell adhesion molecule |
MGP | matrix Gla protein |
MYH10 | myosin, heavy chain 10, non-muscle |
NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
NRN1 | neuritin 1 |
PEG10 | paternally expressed 10 |
PLAT | plasminogen activator, tissue |
PLK1 | polo-like kinase 1 |
PLN | phospholamban |
PLP1 | proteolipid protein 1 |
PLS3 | plastin 3 |
PNMA2 | paraneoplastic Ma antigen 2 |
PODXL | podocalyxin-like |
PPARG | peroxisome proliferator-activated receptor gamma |
PRSS23 | protease, serine, 23 |
PTTG1 | pituitary tumor-transforming 1 |
RGS5 | regulator of G-protein signaling 5 |
RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
SEC14L1 | SEC14-like 1 (S. cerevisiae) |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
STOM | stomatin |
TGM2 | transglutaminase 2 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TSPAN8 | tetraspanin 8 |
TUBB4B | tubulin, beta 4B class IVb |
ZCCHC24 | zinc finger, CCHC domain containing 24 |