| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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118 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADRB2 | adrenoceptor beta 2, surface |
| APOC1 | apolipoprotein C-I |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BAG3 | BCL2-associated athanogene 3 |
| CD52 | CD52 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CLDN3 | claudin 3 |
| CLU | clusterin |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CTSZ | cathepsin Z |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF5A | eukaryotic translation initiation factor 5A |
| FAS | Fas cell surface death receptor |
| FTH1 | ferritin, heavy polypeptide 1 |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| HIST1H2BG | histone cluster 1, H2bg |
| HMOX1 | heme oxygenase 1 |
| HPSE | heparanase |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL7R | interleukin 7 receptor |
| JUN | jun proto-oncogene |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KDM6B | lysine (K)-specific demethylase 6B |
| LBH | limb bud and heart development |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MMP1 | matrix metallopeptidase 1 |
| MT1M | metallothionein 1M |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PEG3 | paternally expressed 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PSAP | prosaposin |
| PTN | pleiotrophin |
| S100A8 | S100 calcium binding protein A8 |
| SCG5 | secretogranin V |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPON1 | spondin 1, extracellular matrix protein |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRGN | serglycin |
| TMEM176B | transmembrane protein 176B |
| TXNIP | thioredoxin interacting protein |
| TXNRD1 | thioredoxin reductase 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AURKB | aurora kinase B |
| BTBD3 | BTB (POZ) domain containing 3 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCNB1 | cyclin B1 |
| CCND1 | cyclin D1 |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CHGB | chromogranin B |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DLD | dihydrolipoamide dehydrogenase |
| EDNRB | endothelin receptor type B |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM3C | family with sequence similarity 3, member C |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HOXA5 | homeobox A5 |
| IER3 | immediate early response 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA6 | integrin, alpha 6 |
| JADE2 | jade family PHD finger 2 |
| KIF20A | kinesin family member 20A |
| KIF2C | kinesin family member 2C |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| LAMB1 | laminin, beta 1 |
| LRRC17 | leucine rich repeat containing 17 |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MCAM | melanoma cell adhesion molecule |
| MGP | matrix Gla protein |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRN1 | neuritin 1 |
| PEG10 | paternally expressed 10 |
| PLAT | plasminogen activator, tissue |
| PLK1 | polo-like kinase 1 |
| PLN | phospholamban |
| PLP1 | proteolipid protein 1 |
| PLS3 | plastin 3 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PODXL | podocalyxin-like |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRSS23 | protease, serine, 23 |
| PTTG1 | pituitary tumor-transforming 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STOM | stomatin |
| TGM2 | transglutaminase 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TSPAN8 | tetraspanin 8 |
| TUBB4B | tubulin, beta 4B class IVb |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
