BRD-K05396879_15-delta prostaglandin J2_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AQP3 aquaporin 3 (Gill blood group)
BAG3 BCL2-associated athanogene 3
BASP1 brain abundant, membrane attached signal protein 1
BID BH3 interacting domain death agonist
C1R complement component 1, r subcomponent
C1S complement component 1, s subcomponent
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CD163 CD163 molecule
CHIC2 cysteine-rich hydrophobic domain 2
CLIC4 chloride intracellular channel 4
CSRP1 cysteine and glycine-rich protein 1
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5A eukaryotic translation initiation factor 5A
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
KYNU kynureninase
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1X metallothionein 1X
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMP22 peripheral myelin protein 22
S100P S100 calcium binding protein P
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D31 TBC1 domain family, member 31
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TMEM176B transmembrane protein 176B
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ALDOA aldolase A, fructose-bisphosphate
ANXA4 annexin A4
ARMCX2 armadillo repeat containing, X-linked 2
ASPH aspartate beta-hydroxylase
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CCND1 cyclin D1
CD24 CD24 molecule
DCK deoxycytidine kinase
ERAP2 endoplasmic reticulum aminopeptidase 2
GPRC5B G protein-coupled receptor, class C, group 5, member B
HES1 hes family bHLH transcription factor 1
INHBA inhibin, beta A
LTBP1 latent transforming growth factor beta binding protein 1
MECOM MDS1 and EVI1 complex locus
PEG10 paternally expressed 10
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
SLAMF7 SLAM family member 7
SPINK1 serine peptidase inhibitor, Kazal type 1
Funding