Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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76 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABHD4 | abhydrolase domain containing 4 |
AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
AKR1C3 | aldo-keto reductase family 1, member C3 |
BAG3 | BCL2-associated athanogene 3 |
BLVRB | biliverdin reductase B |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
CLCA2 | chloride channel accessory 2 |
COL4A5 | collagen, type IV, alpha 5 |
CPB1 | carboxypeptidase B1 (tissue) |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
EFHD1 | EF-hand domain family, member D1 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
FZD7 | frizzled class receptor 7 |
G6PD | glucose-6-phosphate dehydrogenase |
GCLM | glutamate-cysteine ligase, modifier subunit |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
KLF4 | Kruppel-like factor 4 (gut) |
KRT14 | keratin 14, type I |
KRT5 | keratin 5, type II |
KRT6A | keratin 6A, type II |
LRP10 | low density lipoprotein receptor-related protein 10 |
MAP7 | microtubule-associated protein 7 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
NGRN | neugrin, neurite outgrowth associated |
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
PIR | pirin (iron-binding nuclear protein) |
RNF24 | ring finger protein 24 |
SFN | stratifin |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SQSTM1 | sequestosome 1 |
SSBP2 | single-stranded DNA binding protein 2 |
STS | steroid sulfatase (microsomal), isozyme S |
TPD52L1 | tumor protein D52-like 1 |
TRAF5 | TNF receptor-associated factor 5 |
TRIM29 | tripartite motif containing 29 |
TWIST1 | twist family bHLH transcription factor 1 |
TXNRD1 | thioredoxin reductase 1 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
Symbol | Name |
---|---|
AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CLIC3 | chloride intracellular channel 3 |
CRIP1 | cysteine-rich protein 1 (intestinal) |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
GNAS | GNAS complex locus |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HN1 | hematological and neurological expressed 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
IER3 | immediate early response 3 |
IFI6 | interferon, alpha-inducible protein 6 |
IFITM1 | interferon induced transmembrane protein 1 |
IFITM2 | interferon induced transmembrane protein 2 |
IFITM3 | interferon induced transmembrane protein 3 |
ISG15 | ISG15 ubiquitin-like modifier |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
MARCKSL1 | MARCKS-like 1 |
MX1 | MX dynamin-like GTPase 1 |
NUP85 | nucleoporin 85kDa |
PEG3 | paternally expressed 3 |
POLR1C | polymerase (RNA) I polypeptide C, 30kDa |
SIAH2 | siah E3 ubiquitin protein ligase 2 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SRSF6 | serine/arginine-rich splicing factor 6 |
TF | transferrin |
TFF1 | trefoil factor 1 |