BRD-K05396879_15-delta prostaglandin J2_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BAG3 BCL2-associated athanogene 3
BLVRB biliverdin reductase B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCA2 chloride channel accessory 2
COL4A5 collagen, type IV, alpha 5
CPB1 carboxypeptidase B1 (tissue)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EFHD1 EF-hand domain family, member D1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FZD7 frizzled class receptor 7
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLF4 Kruppel-like factor 4 (gut)
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LRP10 low density lipoprotein receptor-related protein 10
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NGRN neugrin, neurite outgrowth associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIR pirin (iron-binding nuclear protein)
RNF24 ring finger protein 24
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SSBP2 single-stranded DNA binding protein 2
STS steroid sulfatase (microsomal), isozyme S
TPD52L1 tumor protein D52-like 1
TRAF5 TNF receptor-associated factor 5
TRIM29 tripartite motif containing 29
TWIST1 twist family bHLH transcription factor 1
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
CCND1 cyclin D1
CD24 CD24 molecule
CLIC3 chloride intracellular channel 3
CRIP1 cysteine-rich protein 1 (intestinal)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
HN1 hematological and neurological expressed 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
ISG15 ISG15 ubiquitin-like modifier
LGALS1 lectin, galactoside-binding, soluble, 1
MARCKSL1 MARCKS-like 1
MX1 MX dynamin-like GTPase 1
NUP85 nucleoporin 85kDa
PEG3 paternally expressed 3
POLR1C polymerase (RNA) I polypeptide C, 30kDa
SIAH2 siah E3 ubiquitin protein ligase 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRSF6 serine/arginine-rich splicing factor 6
TF transferrin
TFF1 trefoil factor 1
Funding