BRD-K05396879_15-delta prostaglandin J2_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
BHLHE40 basic helix-loop-helix family, member e40
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHI3L2 chitinase 3-like 2
CLU clusterin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
ELOVL6 ELOVL fatty acid elongase 6
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
JUN jun proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYC v-myc avian myelocytomatosis viral oncogene homolog
NQO1 NAD(P)H dehydrogenase, quinone 1
PLIN2 perilipin 2
POPDC3 popeye domain containing 3
PPIF peptidylprolyl isomerase F
RET ret proto-oncogene
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPARCL1 SPARC-like 1 (hevin)
SQSTM1 sequestosome 1
TKT transketolase
TUBB2B tubulin, beta 2B class IIb
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
AOX1 aldehyde oxidase 1
ARID5B AT rich interactive domain 5B (MRF1-like)
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CRIP1 cysteine-rich protein 1 (intestinal)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
ERBB2 erb-b2 receptor tyrosine kinase 2
KRT18 keratin 18, type I
MBNL2 muscleblind-like splicing regulator 2
PROM1 prominin 1
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
TM4SF4 transmembrane 4 L six family member 4
TMEM123 transmembrane protein 123
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UXT ubiquitously-expressed, prefoldin-like chaperone
Funding