| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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150 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AK4 | adenylate kinase 4 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ANPEP | alanyl (membrane) aminopeptidase |
| ANXA7 | annexin A7 |
| ATF3 | activating transcription factor 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| BAG3 | BCL2-associated athanogene 3 |
| BLVRB | biliverdin reductase B |
| BMP7 | bone morphogenetic protein 7 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| CA12 | carbonic anhydrase XII |
| CBR1 | carbonyl reductase 1 |
| CBR3 | carbonyl reductase 3 |
| CHPT1 | choline phosphotransferase 1 |
| CLIC1 | chloride intracellular channel 1 |
| CLU | clusterin |
| CTSB | cathepsin B |
| CTSL | cathepsin L |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DSP | desmoplakin |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EIF4E | eukaryotic translation initiation factor 4E |
| EMC3 | ER membrane protein complex subunit 3 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| G6PD | glucose-6-phosphate dehydrogenase |
| GCH1 | GTP cyclohydrolase 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GLA | galactosidase, alpha |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HAS2 | hyaluronan synthase 2 |
| HK1 | hexokinase 1 |
| HMOX1 | heme oxygenase 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KYNU | kynureninase |
| LAMTOR3 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MAB21L2 | mab-21-like 2 (C. elegans) |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MCUR1 | mitochondrial calcium uniporter regulator 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MME | membrane metallo-endopeptidase |
| MMP1 | matrix metallopeptidase 1 |
| MSX1 | msh homeobox 1 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PGRMC1 | progesterone receptor membrane component 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PRDX1 | peroxiredoxin 1 |
| RAB11A | RAB11A, member RAS oncogene family |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| TBX3 | T-box 3 |
| TLR4 | toll-like receptor 4 |
| TNPO1 | transportin 1 |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TRIM16 | tripartite motif containing 16 |
| TXN | thioredoxin |
| TXNRD1 | thioredoxin reductase 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABLIM1 | actin binding LIM protein 1 |
| ACAT2 | acetyl-CoA acetyltransferase 2 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ANKRD10 | ankyrin repeat domain 10 |
| ANOS1 | anosmin 1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| AUTS2 | autism susceptibility candidate 2 |
| C7 | complement component 7 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CDC25B | cell division cycle 25B |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CPE | carboxypeptidase E |
| DAPK1 | death-associated protein kinase 1 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DCN | decorin |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DES | desmin |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EPAS1 | endothelial PAS domain protein 1 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FHL2 | four and a half LIM domains 2 |
| FRY | furry homolog (Drosophila) |
| HOPX | HOP homeobox |
| IFITM1 | interferon induced transmembrane protein 1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) |
| IGKC | immunoglobulin kappa constant |
| IGL | immunoglobulin lambda locus |
| ITM2C | integral membrane protein 2C |
| KLHL41 | kelch-like family member 41 |
| LITAF | lipopolysaccharide-induced TNF factor |
| MAGED2 | melanoma antigen family D2 |
| MARCKSL1 | MARCKS-like 1 |
| MATN2 | matrilin 2 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MT1E | metallothionein 1E |
| MTSS1 | metastasis suppressor 1 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic |
| NEB | nebulin |
| NXN | nucleoredoxin |
| PDLIM3 | PDZ and LIM domain 3 |
| PEG10 | paternally expressed 10 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RGCC | regulator of cell cycle |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPON1 | spondin 1, extracellular matrix protein |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STMN1 | stathmin 1 |
| THBS1 | thrombospondin 1 |
| TMSB15A | thymosin beta 15a |
| TNNC2 | troponin C type 2 (fast) |
| TPM1 | tropomyosin 1 (alpha) |
| TPSAB1 | tryptase alpha/beta 1 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TTC3 | tetratricopeptide repeat domain 3 |
| TTN | titin |
| XIST | X inactive specific transcript (non-protein coding) |
| ZMYND11 | zinc finger, MYND-type containing 11 |
