| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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144 genes differentially expressed following the BRD-K05804044_AZ-628_HCC515_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ABHD4 | abhydrolase domain containing 4 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMACR | alpha-methylacyl-CoA racemase |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| CALD1 | caldesmon 1 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CCDC92 | coiled-coil domain containing 92 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CFB | complement factor B |
| CLIC5 | chloride intracellular channel 5 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTSD | cathepsin D |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEFB1 | defensin, beta 1 |
| DHCR24 | 24-dehydrocholesterol reductase |
| EMP2 | epithelial membrane protein 2 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| FGA | fibrinogen alpha chain |
| FGFR4 | fibroblast growth factor receptor 4 |
| FHL1 | four and a half LIM domains 1 |
| FOLR1 | folate receptor 1 (adult) |
| FSTL1 | follistatin-like 1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS | glutaminase |
| GRAMD1C | GRAM domain containing 1C |
| GSTA1 | glutathione S-transferase alpha 1 |
| HBB | hemoglobin, beta |
| HMOX1 | heme oxygenase 1 |
| HSPB1 | heat shock 27kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| KLF6 | Kruppel-like factor 6 |
| KRT23 | keratin 23, type I |
| LCN2 | lipocalin 2 |
| MAGED1 | melanoma antigen family D1 |
| MAGED2 | melanoma antigen family D2 |
| NDRG3 | NDRG family member 3 |
| OPTN | optineurin |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PDZK1 | PDZ domain containing 1 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PXDN | peroxidasin |
| QPCT | glutaminyl-peptide cyclotransferase |
| REEP1 | receptor accessory protein 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SRGN | serglycin |
| TALDO1 | transaldolase 1 |
| TCTA | T-cell leukemia translocation altered |
| TNS1 | tensin 1 |
| TPM2 | tropomyosin 2 (beta) |
| TSPAN12 | tetraspanin 12 |
| TSPAN13 | tetraspanin 13 |
| TTC39A | tetratricopeptide repeat domain 39A |
| UBE3B | ubiquitin protein ligase E3B |
| VAT1 | vesicle amine transport 1 |
| XYLT1 | xylosyltransferase I |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ADORA2B | adenosine A2b receptor |
| AIM1 | absent in melanoma 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARL4C | ADP-ribosylation factor-like 4C |
| BAG3 | BCL2-associated athanogene 3 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD24 | CD24 molecule |
| CDC20 | cell division cycle 20 |
| CDK4 | cyclin-dependent kinase 4 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| COCH | cochlin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTSH | cathepsin H |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP6 | dual specificity phosphatase 6 |
| DUSP7 | dual specificity phosphatase 7 |
| EGR2 | early growth response 2 |
| EXOSC4 | exosome component 4 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FAM129A | family with sequence similarity 129, member A |
| FOSL1 | FOS-like antigen 1 |
| GAL | galanin/GMAP prepropeptide |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GPM6B | glycoprotein M6B |
| HBEGF | heparin-binding EGF-like growth factor |
| HK2 | hexokinase 2 |
| HMGB2 | high mobility group box 2 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IER3 | immediate early response 3 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RN | interleukin 1 receptor antagonist |
| KIF14 | kinesin family member 14 |
| MT1E | metallothionein 1E |
| MT1G | metallothionein 1G |
| MT1HL1 | metallothionein 1H-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NES | nestin |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NFIB | nuclear factor I/B |
| NMB | neuromedin B |
| NMU | neuromedin U |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAUR | plasminogen activator, urokinase receptor |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| RAB20 | RAB20, member RAS oncogene family |
| RAD51C | RAD51 paralog C |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| SFRP1 | secreted frizzled-related protein 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STX1A | syntaxin 1A (brain) |
| TBX3 | T-box 3 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNC | tenascin C |
| TWIST1 | twist family bHLH transcription factor 1 |
| UPP1 | uridine phosphorylase 1 |
| VCAN | versican |
