BRD-K06009608_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K06009608_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANXA4 annexin A4
CD52 CD52 molecule
CD9 CD9 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CPE carboxypeptidase E
DKK3 dickkopf WNT signaling pathway inhibitor 3
FST follistatin
IL1B interleukin 1, beta
LOC100505650 uncharacterized LOC100505650
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TMEM30B transmembrane protein 30B
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CELF2 CUGBP, Elav-like family member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
FAM57A family with sequence similarity 57, member A
GSPT1 G1 to S phase transition 1
KIF14 kinesin family member 14
KLHL21 kelch-like family member 21
PPIF peptidylprolyl isomerase F
PTGES prostaglandin E synthase
RBPMS RNA binding protein with multiple splicing
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1