BRD-K06180729_DM163 BRD-K06180729_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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53 genes differentially expressed following the BRD-K06180729_DM163 BRD-K06180729_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EYA2 EYA transcriptional coactivator and phosphatase 2
FBLN1 fibulin 1
GJA1 gap junction protein, alpha 1, 43kDa
GPM6A glycoprotein M6A
GRIA2 glutamate receptor, ionotropic, AMPA 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRRN3 leucine rich repeat neuronal 3
MYO10 myosin X
NT5DC2 5'-nucleotidase domain containing 2
NXN nucleoredoxin
PKM pyruvate kinase, muscle
PTN pleiotrophin
RPS4Y1 ribosomal protein S4, Y-linked 1
VDAC3 voltage-dependent anion channel 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ATF5 activating transcription factor 5
BEX4 brain expressed, X-linked 4
CA2 carbonic anhydrase II
CCL19 chemokine (C-C motif) ligand 19
CDK4 cyclin-dependent kinase 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFB complement factor B
CPE carboxypeptidase E
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FABP4 fatty acid binding protein 4, adipocyte
FGF13 fibroblast growth factor 13
FRZB frizzled-related protein
GLIPR1 GLI pathogenesis-related 1
GMFG glia maturation factor, gamma
HIST1H4C histone cluster 1, H4c
LGALS2 lectin, galactoside-binding, soluble, 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MEF2C myocyte enhancer factor 2C
METTL1 methyltransferase like 1
METTL21B methyltransferase like 21B
MGAM maltase-glucoamylase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PI3 peptidase inhibitor 3, skin-derived
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PRKCI protein kinase C, iota
RAP2A RAP2A, member of RAS oncogene family
SFRP1 secreted frizzled-related protein 1
TSPAN31 tetraspanin 31
VNN1 vanin 1
XIST X inactive specific transcript (non-protein coding)