| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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137 genes differentially expressed following the BRD-K06198550_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| APOD | apolipoprotein D |
| AQP3 | aquaporin 3 (Gill blood group) |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| BAG2 | BCL2-associated athanogene 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
| FOLR1 | folate receptor 1 (adult) |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GPX3 | glutathione peroxidase 3 |
| HES1 | hes family bHLH transcription factor 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IER3 | immediate early response 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL6R | interleukin 6 receptor |
| INHBA | inhibin, beta A |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KDM5B | lysine (K)-specific demethylase 5B |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIAA0125 | KIAA0125 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAP7 | microtubule-associated protein 7 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MCL1 | myeloid cell leukemia 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NRIP1 | nuclear receptor interacting protein 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS2 | regulator of G-protein signaling 2 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SF1 | splicing factor 1 |
| SMAD3 | SMAD family member 3 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STK17A | serine/threonine kinase 17a |
| TFF3 | trefoil factor 3 (intestinal) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ADIRF | adipogenesis regulatory factor |
| ANPEP | alanyl (membrane) aminopeptidase |
| ANXA1 | annexin A1 |
| ANXA2 | annexin A2 |
| ANXA4 | annexin A4 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATF5 | activating transcription factor 5 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BEX1 | brain expressed, X-linked 1 |
| BGN | biglycan |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CAV2 | caveolin 2 |
| CD200 | CD200 molecule |
| CD24 | CD24 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CLDN18 | claudin 18 |
| COL1A2 | collagen, type I, alpha 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DCN | decorin |
| DEFB1 | defensin, beta 1 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| EIF5 | eukaryotic translation initiation factor 5 |
| EPAS1 | endothelial PAS domain protein 1 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| EXT1 | exostosin glycosyltransferase 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPNMB | glycoprotein (transmembrane) nmb |
| HELLS | helicase, lymphoid-specific |
| HSPA1A | heat shock 70kDa protein 1A |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IL1R1 | interleukin 1 receptor, type I |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LAMP3 | lysosomal-associated membrane protein 3 |
| MAPT | microtubule-associated protein tau |
| MTSS1 | metastasis suppressor 1 |
| MXRA5 | matrix-remodelling associated 5 |
| NDNF | neuron-derived neurotrophic factor |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTN | pleiotrophin |
| PTPRK | protein tyrosine phosphatase, receptor type, K |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| SERINC5 | serine incorporator 5 |
| SIRPA | signal-regulatory protein alpha |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC35E2B | solute carrier family 35, member E2B |
| SRGN | serglycin |
| SYBU | syntabulin (syntaxin-interacting) |
| TRIM2 | tripartite motif containing 2 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| XIST | X inactive specific transcript (non-protein coding) |
| ZNF395 | zinc finger protein 395 |
