BRD-K06593056_-666_A375_6.0_h_20.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K06593056_-666_A375_6.0_h_20.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
KLF4 Kruppel-like factor 4 (gut)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MPO myeloperoxidase
MT1M metallothionein 1M
PDGFA platelet-derived growth factor alpha polypeptide
PSAT1 phosphoserine aminotransferase 1
S100P S100 calcium binding protein P
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
KIF20A kinesin family member 20A
TOP2A topoisomerase (DNA) II alpha 170kDa