BRD-K06817181_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K06817181_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
COL1A2 collagen, type I, alpha 2
FABP4 fatty acid binding protein 4, adipocyte
GCLM glutamate-cysteine ligase, modifier subunit
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HMOX1 heme oxygenase 1
KCTD12 potassium channel tetramerization domain containing 12
NQO1 NAD(P)H dehydrogenase, quinone 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TXNRD1 thioredoxin reductase 1
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ALB albumin
GNAS GNAS complex locus
GRB14 growth factor receptor-bound protein 14
LGALS1 lectin, galactoside-binding, soluble, 1
PLK1 polo-like kinase 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RPN2 ribophorin II
SPATS2L spermatogenesis associated, serine-rich 2-like