BRD-K07005393_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K07005393_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C3 aldo-keto reductase family 1, member C3
BHLHE41 basic helix-loop-helix family, member e41
CCNA1 cyclin A1
CD200 CD200 molecule
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
CHEK2 checkpoint kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
EDN3 endothelin 3
EIF5A eukaryotic translation initiation factor 5A
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GJA1 gap junction protein, alpha 1, 43kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
KRT18 keratin 18, type I
LPAR1 lysophosphatidic acid receptor 1
RCAN1 regulator of calcineurin 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SQSTM1 sequestosome 1
TFRC transferrin receptor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGF1R insulin-like growth factor 1 receptor
MAN1A1 mannosidase, alpha, class 1A, member 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2