| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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80 genes differentially expressed following the BRD-K07667918_linsitinib_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADIRF | adipogenesis regulatory factor |
| BEX1 | brain expressed, X-linked 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C6ORF62 | chromosome 6 open reading frame 62 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD24 | CD24 molecule |
| CHGB | chromogranin B |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLU | clusterin |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
| EIF5A | eukaryotic translation initiation factor 5A |
| EZR | ezrin |
| FZD7 | frizzled class receptor 7 |
| GNAS | GNAS complex locus |
| HIST1H2AC | histone cluster 1, H2ac |
| HOPX | HOP homeobox |
| HSPA1A | heat shock 70kDa protein 1A |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KLK10 | kallikrein-related peptidase 10 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MT1M | metallothionein 1M |
| MUC1 | mucin 1, cell surface associated |
| NEFL | neurofilament, light polypeptide |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDGFD | platelet derived growth factor D |
| PLIN2 | perilipin 2 |
| PPL | periplakin |
| RAB31 | RAB31, member RAS oncogene family |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RAP1GAP | RAP1 GTPase activating protein |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC38A1 | solute carrier family 38, member 1 |
| TCTA | T-cell leukemia translocation altered |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TPD52L1 | tumor protein D52-like 1 |
| TRIM22 | tripartite motif containing 22 |
| TRIM29 | tripartite motif containing 29 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| UGDH | UDP-glucose 6-dehydrogenase |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| COL1A1 | collagen, type I, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COL6A2 | collagen, type VI, alpha 2 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| EDNRA | endothelin receptor type A |
| EFNB2 | ephrin-B2 |
| EREG | epiregulin |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HLTF | helicase-like transcription factor |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFITM3 | interferon induced transmembrane protein 3 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KYNU | kynureninase |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| NEB | nebulin |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| RBP4 | retinol binding protein 4, plasma |
| RGS2 | regulator of G-protein signaling 2 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SIK1 | salt-inducible kinase 1 |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STK10 | serine/threonine kinase 10 |
| TMEM45A | transmembrane protein 45A |
| TYMS | thymidylate synthetase |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
