| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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63 genes differentially expressed following the BRD-K07667918_linsitinib_MCF10A_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| APOD | apolipoprotein D |
| C3 | complement component 3 |
| CD38 | CD38 molecule |
| CFB | complement factor B |
| CLDN1 | claudin 1 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FBLN1 | fibulin 1 |
| GATA3 | GATA binding protein 3 |
| IL6ST | interleukin 6 signal transducer |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LPL | lipoprotein lipase |
| METTL7A | methyltransferase like 7A |
| MMP7 | matrix metallopeptidase 7 |
| NNMT | nicotinamide N-methyltransferase |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| NTS | neurotensin |
| RGS1 | regulator of G-protein signaling 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SRGN | serglycin |
| STOM | stomatin |
| SYT1 | synaptotagmin I |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| CCND2 | cyclin D2 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DSP | desmoplakin |
| G0S2 | G0/G1 switch 2 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INSIG1 | insulin induced gene 1 |
| JUN | jun proto-oncogene |
| KRT19 | keratin 19, type I |
| KRT8 | keratin 8, type II |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| MYLK | myosin light chain kinase |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| S100A10 | S100 calcium binding protein A10 |
| SDC4 | syndecan 4 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| TLR4 | toll-like receptor 4 |
| TMEM45A | transmembrane protein 45A |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
