BRD-K07667918_linsitinib_MCF7_24_h_3.33_um Gene Set
Genes
45 genes differentially expressed following the BRD-K07667918_linsitinib_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
ABCC3
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
|
|
AREG
|
amphiregulin
|
|
C10ORF10
|
chromosome 10 open reading frame 10
|
|
CCNG2
|
cyclin G2
|
|
CD163
|
CD163 molecule
|
|
CD55
|
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
|
ERBB3
|
erb-b2 receptor tyrosine kinase 3
|
|
ERBB4
|
erb-b2 receptor tyrosine kinase 4
|
|
FOXO4
|
forkhead box O4
|
|
GLUL
|
glutamate-ammonia ligase
|
|
HMOX1
|
heme oxygenase 1
|
|
INHBB
|
inhibin, beta B
|
|
LAMA3
|
laminin, alpha 3
|
|
LAMB3
|
laminin, beta 3
|
|
MFAP2
|
microfibrillar-associated protein 2
|
|
MTSS1
|
metastasis suppressor 1
|
|
MXI1
|
MAX interactor 1, dimerization protein
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
|
NDFIP1
|
Nedd4 family interacting protein 1
|
|
NR4A2
|
nuclear receptor subfamily 4, group A, member 2
|
|
SEPP1
|
selenoprotein P, plasma, 1
|
|
SOX11
|
SRY (sex determining region Y)-box 11
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
|
TXNIP
|
thioredoxin interacting protein
|
|
WDR45
|
WD repeat domain 45
|
decreased expression
| Symbol |
Name |
|
CALM1
|
calmodulin 1 (phosphorylase kinase, delta)
|
|
CEBPG
|
CCAAT/enhancer binding protein (C/EBP), gamma
|
|
COL5A2
|
collagen, type V, alpha 2
|
|
CSTA
|
cystatin A (stefin A)
|
|
EIF5A
|
eukaryotic translation initiation factor 5A
|
|
EPHA3
|
EPH receptor A3
|
|
HSPB8
|
heat shock 22kDa protein 8
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
|
ISG15
|
ISG15 ubiquitin-like modifier
|
|
LTF
|
lactotransferrin
|
|
PCNA
|
proliferating cell nuclear antigen
|
|
PLOD2
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
|
|
PSAT1
|
phosphoserine aminotransferase 1
|
|
PTGDS
|
prostaglandin D2 synthase 21kDa (brain)
|
|
RGS4
|
regulator of G-protein signaling 4
|
|
XIST
|
X inactive specific transcript (non-protein coding)
|
