| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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108 genes differentially expressed following the BRD-K07691486_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| AQP1 | aquaporin 1 (Colton blood group) |
| C6ORF48 | chromosome 6 open reading frame 48 |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CD163 | CD163 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLC | Charcot-Leyden crystal galectin |
| CLEC2B | C-type lectin domain family 2, member B |
| COL11A1 | collagen, type XI, alpha 1 |
| CTGF | connective tissue growth factor |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| EGR3 | early growth response 3 |
| EPHA2 | EPH receptor A2 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM46A | family with sequence similarity 46, member A |
| FASTKD5 | FAST kinase domains 5 |
| FLNB | filamin B, beta |
| FOSL1 | FOS-like antigen 1 |
| FZD6 | frizzled class receptor 6 |
| HIST1H2AC | histone cluster 1, H2ac |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KLHL21 | kelch-like family member 21 |
| KRT14 | keratin 14, type I |
| KRT17 | keratin 17, type I |
| KRT6B | keratin 6B, type II |
| KRT7 | keratin 7, type II |
| LEF1 | lymphoid enhancer-binding factor 1 |
| MCOLN1 | mucolipin 1 |
| MICB | MHC class I polypeptide-related sequence B |
| MXRA5 | matrix-remodelling associated 5 |
| NPY1R | neuropeptide Y receptor Y1 |
| OPN3 | opsin 3 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| POSTN | periostin, osteoblast specific factor |
| PRDX2 | peroxiredoxin 2 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RBP4 | retinol binding protein 4, plasma |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100P | S100 calcium binding protein P |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SESN1 | sestrin 1 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SNAI2 | snail family zinc finger 2 |
| SYNJ2 | synaptojanin 2 |
| TAGLN | transgelin |
| THBS1 | thrombospondin 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TXNIP | thioredoxin interacting protein |
| VGLL4 | vestigial-like family member 4 |
| ZMAT3 | zinc finger, matrin-type 3 |
| Symbol | Name |
|---|---|
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| AURKB | aurora kinase B |
| CASC3 | cancer susceptibility candidate 3 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNA2 | cyclin A2 |
| CCNB2 | cyclin B2 |
| CDC25B | cell division cycle 25B |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CKB | creatine kinase, brain |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| FABP1 | fatty acid binding protein 1, liver |
| FCGBP | Fc fragment of IgG binding protein |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HAMP | hepcidin antimicrobial peptide |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMGB2 | high mobility group box 2 |
| HMGN3 | high mobility group nucleosomal binding domain 3 |
| HOXB7 | homeobox B7 |
| HSPA8 | heat shock 70kDa protein 8 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| JMJD6 | jumonji domain containing 6 |
| KLF2 | Kruppel-like factor 2 |
| LOC100505650 | uncharacterized LOC100505650 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MGLL | monoglyceride lipase |
| NREP | neuronal regeneration related protein |
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) |
| NUP85 | nucleoporin 85kDa |
| PALMD | palmdelphin |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| REEP1 | receptor accessory protein 1 |
| RGS1 | regulator of G-protein signaling 1 |
| RGS5 | regulator of G-protein signaling 5 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| TCF4 | transcription factor 4 |
| TFRC | transferrin receptor |
| TUBA1A | tubulin, alpha 1a |
| TUBB4B | tubulin, beta 4B class IVb |
| WNT5A | wingless-type MMTV integration site family, member 5A |
