| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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127 genes differentially expressed following the BRD-K07691486_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AREG | amphiregulin |
| ARL4C | ADP-ribosylation factor-like 4C |
| BEX4 | brain expressed, X-linked 4 |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CLEC2B | C-type lectin domain family 2, member B |
| CPE | carboxypeptidase E |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DFNA5 | deafness, autosomal dominant 5 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EMP1 | epithelial membrane protein 1 |
| ESR1 | estrogen receptor 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FHL1 | four and a half LIM domains 1 |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST2H2BE | histone cluster 2, H2be |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IER5 | immediate early response 5 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL32 | interleukin 32 |
| ITM2A | integral membrane protein 2A |
| JAG1 | jagged 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MMP10 | matrix metallopeptidase 10 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MYRF | myelin regulatory factor |
| PEG3 | paternally expressed 3 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRNP | prion protein |
| PSAP | prosaposin |
| RAP2C | RAP2C, member of RAS oncogene family |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SESN1 | sestrin 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPON1 | spondin 1, extracellular matrix protein |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TUFT1 | tuftelin 1 |
| TXNL4B | thioredoxin-like 4B |
| WARS | tryptophanyl-tRNA synthetase |
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADI1 | acireductone dioxygenase 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATF5 | activating transcription factor 5 |
| AURKA | aurora kinase A |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CA12 | carbonic anhydrase XII |
| CCNA2 | cyclin A2 |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPF | centromere protein F, 350/400kDa |
| CEP55 | centrosomal protein 55kDa |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 |
| CREB1 | cAMP responsive element binding protein 1 |
| DCN | decorin |
| DEFB1 | defensin, beta 1 |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNM1L | dynamin 1-like |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GNAS | GNAS complex locus |
| GTSE1 | G-2 and S-phase expressed 1 |
| H2AFX | H2A histone family, member X |
| HMGB1 | high mobility group box 1 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXC10 | homeobox C10 |
| HOXC6 | homeobox C6 |
| HP | haptoglobin |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| INTS3 | integrator complex subunit 3 |
| IRS2 | insulin receptor substrate 2 |
| KIF14 | kinesin family member 14 |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| LXN | latexin |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| MSRB1 | methionine sulfoxide reductase B1 |
| MYO6 | myosin VI |
| NEK2 | NIMA-related kinase 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NREP | neuronal regeneration related protein |
| OPN3 | opsin 3 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D31 | TBC1 domain family, member 31 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TMEM100 | transmembrane protein 100 |
| TPR | translocated promoter region, nuclear basket protein |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZWILCH | zwilch kinetochore protein |
