Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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56 genes differentially expressed following the BRD-K07691486_roscovitine_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKAP12 | A kinase (PRKA) anchor protein 12 |
AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
ENO2 | enolase 2 (gamma, neuronal) |
EREG | epiregulin |
GPX3 | glutathione peroxidase 3 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
HSPB8 | heat shock 22kDa protein 8 |
KLF4 | Kruppel-like factor 4 (gut) |
KLK11 | kallikrein-related peptidase 11 |
KRAS | Kirsten rat sarcoma viral oncogene homolog |
LCN2 | lipocalin 2 |
MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
NID2 | nidogen 2 (osteonidogen) |
PAX8 | paired box 8 |
PRUNE2 | prune homolog 2 (Drosophila) |
S100A7 | S100 calcium binding protein A7 |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SULF1 | sulfatase 1 |
Symbol | Name |
---|---|
A2M | alpha-2-macroglobulin |
ASPH | aspartate beta-hydroxylase |
ASPN | asporin |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CD99 | CD99 molecule |
CREM | cAMP responsive element modulator |
FKBP5 | FK506 binding protein 5 |
GNAS | GNAS complex locus |
GNLY | granulysin |
HBB | hemoglobin, beta |
IFITM3 | interferon induced transmembrane protein 3 |
IRS2 | insulin receptor substrate 2 |
KIAA1033 | KIAA1033 |
LUM | lumican |
MCL1 | myeloid cell leukemia 1 |
OLFM1 | olfactomedin 1 |
PEG10 | paternally expressed 10 |
RGCC | regulator of cell cycle |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SFTPA2 | surfactant protein A2 |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TGM2 | transglutaminase 2 |
THBS1 | thrombospondin 1 |
TIMP1 | TIMP metallopeptidase inhibitor 1 |
TM4SF1 | transmembrane 4 L six family member 1 |
TREM1 | triggering receptor expressed on myeloid cells 1 |
TSPAN13 | tetraspanin 13 |
ZYX | zyxin |