BRD-K07996107_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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39 genes differentially expressed following the BRD-K07996107_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD58 CD58 molecule
FOLR1 folate receptor 1 (adult)
HBE1 hemoglobin, epsilon 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KRT15 keratin 15, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MSLN mesothelin
NCK1 NCK adaptor protein 1
NT5E 5'-nucleotidase, ecto (CD73)
P3H2 prolyl 3-hydroxylase 2
PLK2 polo-like kinase 2
PRAME preferentially expressed antigen in melanoma
PRKCB protein kinase C, beta
PTS 6-pyruvoyltetrahydropterin synthase
RPP38 ribonuclease P/MRP 38kDa subunit
SERINC5 serine incorporator 5
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TPD52L1 tumor protein D52-like 1
UBE2A ubiquitin-conjugating enzyme E2A
USP6NL USP6 N-terminal like

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ASCL1 achaete-scute family bHLH transcription factor 1
CD24 CD24 molecule
DPYSL3 dihydropyrimidinase-like 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GLUL glutamate-ammonia ligase
INSM1 insulinoma-associated 1
JUN jun proto-oncogene
NFIB nuclear factor I/B
PBX1 pre-B-cell leukemia homeobox 1
PHACTR2 phosphatase and actin regulator 2
PROSC proline synthetase co-transcribed homolog (bacterial)
S100P S100 calcium binding protein P
TIMP4 TIMP metallopeptidase inhibitor 4
TUBB2B tubulin, beta 2B class IIb