| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
119 genes differentially expressed following the BRD-K08109215_I-BET_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ASS1 | argininosuccinate synthase 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CD24 | CD24 molecule |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DSP | desmoplakin |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GATA3 | GATA binding protein 3 |
| GOLGA8H | golgin A8 family, member H |
| HEBP1 | heme binding protein 1 |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HOXA5 | homeobox A5 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| JAK1 | Janus kinase 1 |
| KIF2C | kinesin family member 2C |
| KLF4 | Kruppel-like factor 4 (gut) |
| LCN2 | lipocalin 2 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NID2 | nidogen 2 (osteonidogen) |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ORM1 | orosomucoid 1 |
| PKP2 | plakophilin 2 |
| PLXNC1 | plexin C1 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| REC8 | REC8 meiotic recombination protein |
| RTN3 | reticulon 3 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SF1 | splicing factor 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STXBP1 | syntaxin binding protein 1 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| TXNRD1 | thioredoxin reductase 1 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VNN1 | vanin 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| ANPEP | alanyl (membrane) aminopeptidase |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP13A3 | ATPase type 13A3 |
| AUTS2 | autism susceptibility candidate 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CBR3 | carbonyl reductase 3 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD163 | CD163 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| COL3A1 | collagen, type III, alpha 1 |
| CRYAB | crystallin, alpha B |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYTH1 | cytohesin 1 |
| EDN1 | endothelin 1 |
| EGF | epidermal growth factor |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOSL1 | FOS-like antigen 1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOPX | HOP homeobox |
| ICAM1 | intercellular adhesion molecule 1 |
| IFRD2 | interferon-related developmental regulator 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IGLJ3 | immunoglobulin lambda joining 3 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KRT17 | keratin 17, type I |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOX | lysyl oxidase |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| PDLIM5 | PDZ and LIM domain 5 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLTP | phospholipid transfer protein |
| PRKCA | protein kinase C, alpha |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB25 | RAB25, member RAS oncogene family |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| S100A10 | S100 calcium binding protein A10 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLAMF8 | SLAM family member 8 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TPM1 | tropomyosin 1 (alpha) |
| TPM4 | tropomyosin 4 |
| TRBC1 | T cell receptor beta constant 1 |
| VEGFA | vascular endothelial growth factor A |
| WDR1 | WD repeat domain 1 |
| XBP1 | X-box binding protein 1 |
| XPO7 | exportin 7 |
