Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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89 genes differentially expressed following the BRD-K08502430_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATF3 | activating transcription factor 3 |
ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
CD52 | CD52 molecule |
CD9 | CD9 molecule |
CPA3 | carboxypeptidase A3 (mast cell) |
CTBP2 | C-terminal binding protein 2 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL11 | chemokine (C-X-C motif) ligand 11 |
DDIT4 | DNA-damage-inducible transcript 4 |
DPT | dermatopontin |
EREG | epiregulin |
F11R | F11 receptor |
FAM129A | family with sequence similarity 129, member A |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FGFR1 | fibroblast growth factor receptor 1 |
GAL | galanin/GMAP prepropeptide |
GARS | glycyl-tRNA synthetase |
GEM | GTP binding protein overexpressed in skeletal muscle |
GPNMB | glycoprotein (transmembrane) nmb |
GRB10 | growth factor receptor-bound protein 10 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IDO1 | indoleamine 2,3-dioxygenase 1 |
IER3 | immediate early response 3 |
IFRD1 | interferon-related developmental regulator 1 |
JAG1 | jagged 1 |
LMO3 | LIM domain only 3 (rhombotin-like 2) |
LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MME | membrane metallo-endopeptidase |
MT1E | metallothionein 1E |
MT1M | metallothionein 1M |
MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
MX1 | MX dynamin-like GTPase 1 |
NUPL1 | nucleoporin like 1 |
PEA15 | phosphoprotein enriched in astrocytes 15 |
PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
PWP1 | PWP1 homolog (S. cerevisiae) |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SIK1 | salt-inducible kinase 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TRIB3 | tribbles pseudokinase 3 |
XIST | X inactive specific transcript (non-protein coding) |
YARS | tyrosyl-tRNA synthetase |
Symbol | Name |
---|---|
ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
ACOX2 | acyl-CoA oxidase 2, branched chain |
AMDHD2 | amidohydrolase domain containing 2 |
ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
ANXA6 | annexin A6 |
BIRC5 | baculoviral IAP repeat containing 5 |
BRCA1 | breast cancer 1, early onset |
CASP2 | caspase 2, apoptosis-related cysteine peptidase |
CCNA2 | cyclin A2 |
CDC25B | cell division cycle 25B |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CENPA | centromere protein A |
CRYAB | crystallin, alpha B |
CTSH | cathepsin H |
CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
DCXR | dicarbonyl/L-xylulose reductase |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EFNA1 | ephrin-A1 |
GPX3 | glutathione peroxidase 3 |
HSPA1A | heat shock 70kDa protein 1A |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
KRT19 | keratin 19, type I |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MEF2C | myocyte enhancer factor 2C |
PLK1 | polo-like kinase 1 |
PROM1 | prominin 1 |
QPRT | quinolinate phosphoribosyltransferase |
REEP1 | receptor accessory protein 1 |
RHOBTB3 | Rho-related BTB domain containing 3 |
RPL37A | ribosomal protein L37a |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SORBS3 | sorbin and SH3 domain containing 3 |
SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
STXBP2 | syntaxin binding protein 2 |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
TF | transferrin |
TP53 | tumor protein p53 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |