BRD-K08589866_OSI-906_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K08589866_OSI-906_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ALOX5 arachidonate 5-lipoxygenase
ARHGAP29 Rho GTPase activating protein 29
C3 complement component 3
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CFB complement factor B
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
GBP2 guanylate binding protein 2, interferon-inducible
HHEX hematopoietically expressed homeobox
KLHL24 kelch-like family member 24
KRT23 keratin 23, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MTUS1 microtubule associated tumor suppressor 1
NEBL nebulette
NNMT nicotinamide N-methyltransferase
PTPRC protein tyrosine phosphatase, receptor type, C
SOD2 superoxide dismutase 2, mitochondrial
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TF transferrin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TRIM38 tripartite motif containing 38
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
AP2B1 adaptor-related protein complex 2, beta 1 subunit
BCL2A1 BCL2-related protein A1
CCND1 cyclin D1
FAM57A family with sequence similarity 57, member A
G0S2 G0/G1 switch 2
LPL lipoprotein lipase
MAP1B microtubule-associated protein 1B
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SRSF7 serine/arginine-rich splicing factor 7
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
Funding