BRD-K09778810_FGIN-1-27_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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79 genes differentially expressed following the BRD-K09778810_FGIN-1-27_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCR7 chemokine (C-C motif) receptor 7
CD24 CD24 molecule
CFD complement factor D (adipsin)
CLDN3 claudin 3
CRIP1 cysteine-rich protein 1 (intestinal)
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EFHD1 EF-hand domain family, member D1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS3 fatty acid desaturase 3
FNDC3B fibronectin type III domain containing 3B
FST follistatin
GPX4 glutathione peroxidase 4
HNMT histamine N-methyltransferase
HOXB6 homeobox B6
HOXB7 homeobox B7
IFITM1 interferon induced transmembrane protein 1
IGFBP6 insulin-like growth factor binding protein 6
ITGAV integrin, alpha V
MAN1A1 mannosidase, alpha, class 1A, member 1
MOK MOK protein kinase
MTSS1 metastasis suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
PAX6 paired box 6
PERP PERP, TP53 apoptosis effector
PLAU plasminogen activator, urokinase
REG1B regenerating islet-derived 1 beta
RNF167 ring finger protein 167
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMAD3 SMAD family member 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TGFBR3 transforming growth factor, beta receptor III
TMEM123 transmembrane protein 123
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VEGFC vascular endothelial growth factor C

decreased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD10 ankyrin repeat domain 10
BCLAF1 BCL2-associated transcription factor 1
BRD2 bromodomain containing 2
C8ORF4 chromosome 8 open reading frame 4
CCND2 cyclin D2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CHL1 cell adhesion molecule L1-like
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EIF5 eukaryotic translation initiation factor 5
ENOPH1 enolase-phosphatase 1
FOLR1 folate receptor 1 (adult)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPM6B glycoprotein M6B
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HSPH1 heat shock 105kDa/110kDa protein 1
IL6R interleukin 6 receptor
INPP5F inositol polyphosphate-5-phosphatase F
LEF1 lymphoid enhancer-binding factor 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPT microtubule-associated protein tau
MRPS30 mitochondrial ribosomal protein S30
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
PCDH9 protocadherin 9
PON2 paraoxonase 2
PPAT phosphoribosyl pyrophosphate amidotransferase
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
SPATS2L spermatogenesis associated, serine-rich 2-like
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TCF4 transcription factor 4