BRD-K09778810_FGIN-1-27_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

37 genes differentially expressed following the BRD-K09778810_FGIN-1-27_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COL4A5 collagen, type IV, alpha 5
CRYM crystallin, mu
CXCL8 chemokine (C-X-C motif) ligand 8
DSP desmoplakin
FN1 fibronectin 1
FZD6 frizzled class receptor 6
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
IGFBP5 insulin-like growth factor binding protein 5
KRT7 keratin 7, type II
LOC100505650 uncharacterized LOC100505650
PDZK1 PDZ domain containing 1
PPAP2B phosphatidic acid phosphatase type 2B
PTPRO protein tyrosine phosphatase, receptor type, O
PTX3 pentraxin 3, long
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SNAP25 synaptosomal-associated protein, 25kDa
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
THBS1 thrombospondin 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
CFD complement factor D (adipsin)
HOXA5 homeobox A5
IGF1 insulin-like growth factor 1 (somatomedin C)
INSIG1 insulin induced gene 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MSMO1 methylsterol monooxygenase 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SDCBP syndecan binding protein (syntenin)
SEC61G Sec61 gamma subunit
SNRPE small nuclear ribonucleoprotein polypeptide E
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TBC1D4 TBC1 domain family, member 4
TMSB15A thymosin beta 15a