Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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97 genes differentially expressed following the BRD-K09991945_GSK-3-inhibitor-II_HT29_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
AGR2 | anterior gradient 2 |
ANO10 | anoctamin 10 |
AREG | amphiregulin |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
CCL4 | chemokine (C-C motif) ligand 4 |
CCND1 | cyclin D1 |
CD3D | CD3d molecule, delta (CD3-TCR complex) |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
DSP | desmoplakin |
ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
EPCAM | epithelial cell adhesion molecule |
FGFR3 | fibroblast growth factor receptor 3 |
GDF15 | growth differentiation factor 15 |
GLDC | glycine dehydrogenase (decarboxylating) |
GOLM1 | golgi membrane protein 1 |
GSTM1 | glutathione S-transferase mu 1 |
GSTM2 | glutathione S-transferase mu 2 (muscle) |
HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
HN1 | hematological and neurological expressed 1 |
ICAM1 | intercellular adhesion molecule 1 |
IGLV2-23 | immunoglobulin lambda variable 2-23 |
IL32 | interleukin 32 |
IL6R | interleukin 6 receptor |
ISOC1 | isochorismatase domain containing 1 |
NAP1L3 | nucleosome assembly protein 1-like 3 |
PNMA1 | paraneoplastic Ma antigen 1 |
PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
PTCH1 | patched 1 |
PTGDS | prostaglandin D2 synthase 21kDa (brain) |
RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
RGS1 | regulator of G-protein signaling 1 |
RHOF | ras homolog family member F (in filopodia) |
SEPP1 | selenoprotein P, plasma, 1 |
SH2D1A | SH2 domain containing 1A |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
TFRC | transferrin receptor |
TM4SF1 | transmembrane 4 L six family member 1 |
TM9SF3 | transmembrane 9 superfamily member 3 |
TP53 | tumor protein p53 |
TRBC1 | T cell receptor beta constant 1 |
VAMP8 | vesicle-associated membrane protein 8 |
ZMAT3 | zinc finger, matrin-type 3 |
Symbol | Name |
---|---|
ADM | adrenomedullin |
APOD | apolipoprotein D |
BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
BLNK | B-cell linker |
CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CLCA2 | chloride channel accessory 2 |
CNN3 | calponin 3, acidic |
CRELD2 | cysteine-rich with EGF-like domains 2 |
CSTA | cystatin A (stefin A) |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
FAM129A | family with sequence similarity 129, member A |
GJA1 | gap junction protein, alpha 1, 43kDa |
HLA-DOB | major histocompatibility complex, class II, DO beta |
HLA-DRA | major histocompatibility complex, class II, DR alpha |
HOXC6 | homeobox C6 |
IFI16 | interferon, gamma-inducible protein 16 |
IFI44 | interferon-induced protein 44 |
IPO13 | importin 13 |
KIAA0226L | KIAA0226-like |
KLK5 | kallikrein-related peptidase 5 |
LOX | lysyl oxidase |
LRMP | lymphoid-restricted membrane protein |
MEIS2 | Meis homeobox 2 |
NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
NSG1 | neuron specific gene family member 1 |
OSBPL10 | oxysterol binding protein-like 10 |
PAX5 | paired box 5 |
PBX3 | pre-B-cell leukemia homeobox 3 |
PCP4 | Purkinje cell protein 4 |
PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
PRUNE2 | prune homolog 2 (Drosophila) |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
RNH1 | ribonuclease/angiogenin inhibitor 1 |
S100A8 | S100 calcium binding protein A8 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SHB | Src homology 2 domain containing adaptor protein B |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
STC1 | stanniocalcin 1 |
SWAP70 | SWAP switching B-cell complex 70kDa subunit |
TPM2 | tropomyosin 2 (beta) |
TRIB2 | tribbles pseudokinase 2 |
TRIM2 | tripartite motif containing 2 |
UGCG | UDP-glucose ceramide glucosyltransferase |
VPREB3 | pre-B lymphocyte 3 |
ZNF395 | zinc finger protein 395 |