| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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61 genes differentially expressed following the BRD-K10705233_GW405833 hydrochloride_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTG2 | BTG family, member 2 |
| CD8A | CD8a molecule |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLDN1 | claudin 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| IFI16 | interferon, gamma-inducible protein 16 |
| JAG1 | jagged 1 |
| KRT81 | keratin 81, type II |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCP4 | Purkinje cell protein 4 |
| PHGDH | phosphoglycerate dehydrogenase |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQSTM1 | sequestosome 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TF | transferrin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| Symbol | Name |
|---|---|
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CDC25A | cell division cycle 25A |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPU | centromere protein U |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| EMP2 | epithelial membrane protein 2 |
| EVL | Enah/Vasp-like |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| H2AFX | H2A histone family, member X |
| HIST1H4C | histone cluster 1, H4c |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HN1 | hematological and neurological expressed 1 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| KIF20A | kinesin family member 20A |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MCM6 | minichromosome maintenance complex component 6 |
| PRC1 | protein regulator of cytokinesis 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RRM2 | ribonucleotide reductase M2 |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| TYMS | thymidylate synthetase |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| ZWINT | ZW10 interacting kinetochore protein |
