| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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156 genes differentially expressed following the BRD-K10705233_GW405833 hydrochloride_SKMEL1_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTN1 | actinin, alpha 1 |
| AIM1 | absent in melanoma 1 |
| ALB | albumin |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA1 | annexin A1 |
| APP | amyloid beta (A4) precursor protein |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CADM1 | cell adhesion molecule 1 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD302 | CD302 molecule |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP57 | centrosomal protein 57kDa |
| CHN2 | chimerin 2 |
| COG7 | component of oligomeric golgi complex 7 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DENND1B | DENN/MADD domain containing 1B |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPHA3 | EPH receptor A3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM129A | family with sequence similarity 129, member A |
| FCGBP | Fc fragment of IgG binding protein |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IL17RB | interleukin 17 receptor B |
| IPO13 | importin 13 |
| KRT19 | keratin 19, type I |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LOXL2 | lysyl oxidase-like 2 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRC17 | leucine rich repeat containing 17 |
| LYZ | lysozyme |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MEIS2 | Meis homeobox 2 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MXRA5 | matrix-remodelling associated 5 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NCAM1 | neural cell adhesion molecule 1 |
| NELL2 | NEL-like 2 (chicken) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PDE8B | phosphodiesterase 8B |
| PEG10 | paternally expressed 10 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POSTN | periostin, osteoblast specific factor |
| PRUNE | prune exopolyphosphatase |
| RAB25 | RAB25, member RAS oncogene family |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| S100P | S100 calcium binding protein P |
| SDC2 | syndecan 2 |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| TF | transferrin |
| TMEM30B | transmembrane protein 30B |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VEGFA | vascular endothelial growth factor A |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABLIM1 | actin binding LIM protein 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
| ALDOA | aldolase A, fructose-bisphosphate |
| AMACR | alpha-methylacyl-CoA racemase |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BAALC | brain and acute leukemia, cytoplasmic |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CCND1 | cyclin D1 |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLIC4 | chloride intracellular channel 4 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CLU | clusterin |
| CRYAB | crystallin, alpha B |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DUSP1 | dual specificity phosphatase 1 |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ETNK1 | ethanolamine kinase 1 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FHL1 | four and a half LIM domains 1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GAL | galanin/GMAP prepropeptide |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTP1 | glutathione S-transferase pi 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HN1 | hematological and neurological expressed 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| KIAA0125 | KIAA0125 |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAP7 | microtubule-associated protein 7 |
| MGST3 | microsomal glutathione S-transferase 3 |
| MIPEP | mitochondrial intermediate peptidase |
| MRPS30 | mitochondrial ribosomal protein S30 |
| ODC1 | ornithine decarboxylase 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PFKP | phosphofructokinase, platelet |
| PIP | prolactin-induced protein |
| PRDX1 | peroxiredoxin 1 |
| PSPH | phosphoserine phosphatase |
| QDPR | quinoid dihydropteridine reductase |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RGS5 | regulator of G-protein signaling 5 |
| RPL37A | ribosomal protein L37a |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM14A | transmembrane protein 14A |
| TMSB15A | thymosin beta 15a |
| TSC22D1 | TSC22 domain family, member 1 |
| TUBA1A | tubulin, alpha 1a |
| TUBB2A | tubulin, beta 2A class IIa |
| TUBB2B | tubulin, beta 2B class IIb |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| UBE3C | ubiquitin protein ligase E3C |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VCAM1 | vascular cell adhesion molecule 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
