| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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43 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_A375_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CYB5R1 | cytochrome b5 reductase 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGL | immunoglobulin lambda locus |
| ISG15 | ISG15 ubiquitin-like modifier |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PIR | pirin (iron-binding nuclear protein) |
| PSPH | phosphoserine phosphatase |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| SFN | stratifin |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| WIF1 | WNT inhibitory factor 1 |
| Symbol | Name |
|---|---|
| AURKA | aurora kinase A |
| BAMBI | BMP and activin membrane-bound inhibitor |
| CCNA2 | cyclin A2 |
| CENPA | centromere protein A |
| IER3 | immediate early response 3 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IRS2 | insulin receptor substrate 2 |
| LAMB1 | laminin, beta 1 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) |
| MID1 | midline 1 |
| MOK | MOK protein kinase |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| SDC2 | syndecan 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM2 | transmembrane protein 2 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
