Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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115 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_A673_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ANPEP | alanyl (membrane) aminopeptidase |
ANXA5 | annexin A5 |
AQP9 | aquaporin 9 |
ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
BHLHE40 | basic helix-loop-helix family, member e40 |
BIN1 | bridging integrator 1 |
CD14 | CD14 molecule |
CLMN | calmin (calponin-like, transmembrane) |
CTSH | cathepsin H |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDIT4 | DNA-damage-inducible transcript 4 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FOSL1 | FOS-like antigen 1 |
FUCA1 | fucosidase, alpha-L- 1, tissue |
GCLM | glutamate-cysteine ligase, modifier subunit |
GLUL | glutamate-ammonia ligase |
HBEGF | heparin-binding EGF-like growth factor |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMOX1 | heme oxygenase 1 |
HPSE | heparanase |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IDI1 | isopentenyl-diphosphate delta isomerase 1 |
IGHMBP2 | immunoglobulin mu binding protein 2 |
INSIG1 | insulin induced gene 1 |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
LPAR2 | lysophosphatidic acid receptor 2 |
MAGEA12 | melanoma antigen family A12 |
MME | membrane metallo-endopeptidase |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PIH1D1 | PIH1 domain containing 1 |
PIR | pirin (iron-binding nuclear protein) |
PRSS3 | protease, serine, 3 |
RAB20 | RAB20, member RAS oncogene family |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
SLC35E3 | solute carrier family 35, member E3 |
SLC35F2 | solute carrier family 35, member F2 |
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
TMEM97 | transmembrane protein 97 |
TYMP | thymidine phosphorylase |
VEGFA | vascular endothelial growth factor A |
WSB1 | WD repeat and SOCS box containing 1 |
XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
ZBTB18 | zinc finger and BTB domain containing 18 |
Symbol | Name |
---|---|
AMIGO2 | adhesion molecule with Ig-like domain 2 |
ANOS1 | anosmin 1 |
ANXA1 | annexin A1 |
AREG | amphiregulin |
AUTS2 | autism susceptibility candidate 2 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
BTBD3 | BTB (POZ) domain containing 3 |
CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
CCNE2 | cyclin E2 |
CD24 | CD24 molecule |
CLIC4 | chloride intracellular channel 4 |
CRABP1 | cellular retinoic acid binding protein 1 |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CSRP1 | cysteine and glycine-rich protein 1 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
CYTIP | cytohesin 1 interacting protein |
CYTL1 | cytokine-like 1 |
DEPTOR | DEP domain containing MTOR-interacting protein |
DPH2 | DPH2 homolog (S. cerevisiae) |
DPYSL3 | dihydropyrimidinase-like 3 |
FABP4 | fatty acid binding protein 4, adipocyte |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FZD7 | frizzled class receptor 7 |
GPC4 | glypican 4 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
IDO1 | indoleamine 2,3-dioxygenase 1 |
IER3 | immediate early response 3 |
ITGA6 | integrin, alpha 6 |
ITM2A | integral membrane protein 2A |
KRT7 | keratin 7, type II |
LPL | lipoprotein lipase |
LXN | latexin |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
MAP7 | microtubule-associated protein 7 |
NNMT | nicotinamide N-methyltransferase |
NTS | neurotensin |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PODXL | podocalyxin-like |
RAB31 | RAB31, member RAS oncogene family |
SATB2 | SATB homeobox 2 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
SESN1 | sestrin 1 |
SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
SOX2 | SRY (sex determining region Y)-box 2 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPEN | spen family transcriptional repressor |
STOM | stomatin |
TGM2 | transglutaminase 2 |
TNC | tenascin C |
TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
TRIM22 | tripartite motif containing 22 |
TXNDC9 | thioredoxin domain containing 9 |
VGLL4 | vestigial-like family member 4 |
VSNL1 | visinin-like 1 |
XIST | X inactive specific transcript (non-protein coding) |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
ZW10 | zw10 kinetochore protein |