Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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112 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_DV90_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C1 | aldo-keto reductase family 1, member C1 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
BAG3 | BCL2-associated athanogene 3 |
C14ORF132 | chromosome 14 open reading frame 132 |
CADM1 | cell adhesion molecule 1 |
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
CST1 | cystatin SN |
CTSZ | cathepsin Z |
DDIT4 | DNA-damage-inducible transcript 4 |
DENND5A | DENN/MADD domain containing 5A |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DMTF1 | cyclin D binding myb-like transcription factor 1 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DPT | dermatopontin |
DUSP1 | dual specificity phosphatase 1 |
EFS | embryonal Fyn-associated substrate |
FADS1 | fatty acid desaturase 1 |
FHL2 | four and a half LIM domains 2 |
FOLR1 | folate receptor 1 (adult) |
FOSL1 | FOS-like antigen 1 |
FTH1 | ferritin, heavy polypeptide 1 |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IFI27 | interferon, alpha-inducible protein 27 |
IFI6 | interferon, alpha-inducible protein 6 |
JUN | jun proto-oncogene |
KRT5 | keratin 5, type II |
MAP1B | microtubule-associated protein 1B |
MLF1 | myeloid leukemia factor 1 |
MMP1 | matrix metallopeptidase 1 |
MMP12 | matrix metallopeptidase 12 |
NEFH | neurofilament, heavy polypeptide |
NQO1 | NAD(P)H dehydrogenase, quinone 1 |
PEG3 | paternally expressed 3 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
RGS5 | regulator of G-protein signaling 5 |
RHOB | ras homolog family member B |
RPS11 | ribosomal protein S11 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SFN | stratifin |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SORBS1 | sorbin and SH3 domain containing 1 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
SULF1 | sulfatase 1 |
TBX3 | T-box 3 |
TMEM41B | transmembrane protein 41B |
TPP1 | tripeptidyl peptidase I |
TXNRD1 | thioredoxin reductase 1 |
VWF | von Willebrand factor |
ZNF423 | zinc finger protein 423 |
Symbol | Name |
---|---|
ACSL1 | acyl-CoA synthetase long-chain family member 1 |
ALDOB | aldolase B, fructose-bisphosphate |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
CCND1 | cyclin D1 |
CD24 | CD24 molecule |
CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CXCL14 | chemokine (C-X-C motif) ligand 14 |
CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
DCLK1 | doublecortin-like kinase 1 |
DUOX2 | dual oxidase 2 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GOLGA8A | golgin A8 family, member A |
GOLGA8H | golgin A8 family, member H |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
HHEX | hematopoietically expressed homeobox |
HMG20B | high mobility group 20B |
HOXC6 | homeobox C6 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGL | immunoglobulin lambda locus |
KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
LMO2 | LIM domain only 2 (rhombotin-like 1) |
MFSD10 | major facilitator superfamily domain containing 10 |
MRPS2 | mitochondrial ribosomal protein S2 |
MUC1 | mucin 1, cell surface associated |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
NNT | nicotinamide nucleotide transhydrogenase |
ORC1 | origin recognition complex, subunit 1 |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PCSK6 | proprotein convertase subtilisin/kexin type 6 |
PDZK1IP1 | PDZK1 interacting protein 1 |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
PRR15L | proline rich 15-like |
PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
SDC2 | syndecan 2 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
SOX4 | SRY (sex determining region Y)-box 4 |
SUN1 | Sad1 and UNC84 domain containing 1 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TFF1 | trefoil factor 1 |
TMEM176B | transmembrane protein 176B |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
WNT5A | wingless-type MMTV integration site family, member 5A |