Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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131 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_EFO27_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C3 | aldo-keto reductase family 1, member C3 |
ALOX5 | arachidonate 5-lipoxygenase |
C10ORF10 | chromosome 10 open reading frame 10 |
C2 | complement component 2 |
C5AR1 | complement component 5a receptor 1 |
CES2 | carboxylesterase 2 |
CLEC7A | C-type lectin domain family 7, member A |
CTBS | chitobiase, di-N-acetyl- |
CTSE | cathepsin E |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DDIT4 | DNA-damage-inducible transcript 4 |
DHCR24 | 24-dehydrocholesterol reductase |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DPYD | dihydropyrimidine dehydrogenase |
DSP | desmoplakin |
DYNLT3 | dynein, light chain, Tctex-type 3 |
EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
FAM107A | family with sequence similarity 107, member A |
FGR | FGR proto-oncogene, Src family tyrosine kinase |
FN1 | fibronectin 1 |
FPR1 | formyl peptide receptor 1 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GNAS | GNAS complex locus |
GRB10 | growth factor receptor-bound protein 10 |
HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMOX1 | heme oxygenase 1 |
HOPX | HOP homeobox |
HPCAL1 | hippocalcin-like 1 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
IL15 | interleukin 15 |
IPO13 | importin 13 |
KCTD12 | potassium channel tetramerization domain containing 12 |
KRT14 | keratin 14, type I |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
LIMCH1 | LIM and calponin homology domains 1 |
MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase |
MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
MECOM | MDS1 and EVI1 complex locus |
MSR1 | macrophage scavenger receptor 1 |
MXI1 | MAX interactor 1, dimerization protein |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NAMPT | nicotinamide phosphoribosyltransferase |
NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
NEBL | nebulette |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PSPH | phosphoserine phosphatase |
PTPRC | protein tyrosine phosphatase, receptor type, C |
RGCC | regulator of cell cycle |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
SNX10 | sorting nexin 10 |
ST18 | suppression of tumorigenicity 18, zinc finger |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TLR4 | toll-like receptor 4 |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
UBE2B | ubiquitin-conjugating enzyme E2B |
UFM1 | ubiquitin-fold modifier 1 |
VNN1 | vanin 1 |
WFDC1 | WAP four-disulfide core domain 1 |
ZBTB16 | zinc finger and BTB domain containing 16 |
Symbol | Name |
---|---|
AKAP12 | A kinase (PRKA) anchor protein 12 |
ALCAM | activated leukocyte cell adhesion molecule |
ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
ANO1 | anoctamin 1, calcium activated chloride channel |
ANXA6 | annexin A6 |
AURKA | aurora kinase A |
CA1 | carbonic anhydrase I |
CARD10 | caspase recruitment domain family, member 10 |
CCNA1 | cyclin A1 |
CCND1 | cyclin D1 |
CD19 | CD19 molecule |
CD79A | CD79a molecule, immunoglobulin-associated alpha |
CDC20 | cell division cycle 20 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
DLK1 | delta-like 1 homolog (Drosophila) |
EZR | ezrin |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FADS2 | fatty acid desaturase 2 |
FRZB | frizzled-related protein |
GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
GREM1 | gremlin 1, DAN family BMP antagonist |
GRWD1 | glutamate-rich WD repeat containing 1 |
HBD | hemoglobin, delta |
HMGB2 | high mobility group box 2 |
HNRNPL | heterogeneous nuclear ribonucleoprotein L |
HOXC6 | homeobox C6 |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
MATN2 | matrilin 2 |
MMP7 | matrix metallopeptidase 7 |
MMP9 | matrix metallopeptidase 9 |
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
NEK2 | NIMA-related kinase 2 |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NPIPB3 | nuclear pore complex interacting protein family, member B3 |
NT5E | 5'-nucleotidase, ecto (CD73) |
NUP98 | nucleoporin 98kDa |
ODC1 | ornithine decarboxylase 1 |
OSBPL10 | oxysterol binding protein-like 10 |
PARP2 | poly (ADP-ribose) polymerase 2 |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PLK1 | polo-like kinase 1 |
PNN | pinin, desmosome associated protein |
PROM1 | prominin 1 |
PTCH1 | patched 1 |
RAD23B | RAD23 homolog B (S. cerevisiae) |
RCAN2 | regulator of calcineurin 2 |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RHOBTB3 | Rho-related BTB domain containing 3 |
S100P | S100 calcium binding protein P |
SFRP1 | secreted frizzled-related protein 1 |
SFRP4 | secreted frizzled-related protein 4 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SRSF6 | serine/arginine-rich splicing factor 6 |
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
TESC | tescalcin |
TFF1 | trefoil factor 1 |
TFF3 | trefoil factor 3 (intestinal) |
TMX4 | thioredoxin-related transmembrane protein 4 |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
VCAN | versican |