Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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50 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_HA1E_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
BAG3 | BCL2-associated athanogene 3 |
BCL6 | B-cell CLL/lymphoma 6 |
BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
CD52 | CD52 molecule |
CTH | cystathionine gamma-lyase |
DDIT4 | DNA-damage-inducible transcript 4 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
GPI | glucose-6-phosphate isomerase |
HK2 | hexokinase 2 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
INSIG1 | insulin induced gene 1 |
KDM5D | lysine (K)-specific demethylase 5D |
MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
MUC4 | mucin 4, cell surface associated |
NEFL | neurofilament, light polypeptide |
NQO2 | NAD(P)H dehydrogenase, quinone 2 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
AHR | aryl hydrocarbon receptor |
BMI1 | BMI1 proto-oncogene, polycomb ring finger |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CBR3 | carbonyl reductase 3 |
CCL2 | chemokine (C-C motif) ligand 2 |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
CYTH1 | cytohesin 1 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
HOXA10 | homeobox A10 |
HOXA5 | homeobox A5 |
IER3 | immediate early response 3 |
LAMP5 | lysosomal-associated membrane protein family, member 5 |
LIMA1 | LIM domain and actin binding 1 |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
PALLD | palladin, cytoskeletal associated protein |
PBX3 | pre-B-cell leukemia homeobox 3 |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RHOBTB3 | Rho-related BTB domain containing 3 |
SDC2 | syndecan 2 |
SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
SOX4 | SRY (sex determining region Y)-box 4 |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TFRC | transferrin receptor |
XIST | X inactive specific transcript (non-protein coding) |