| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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126 genes differentially expressed following the BRD-K10882151_BO2 (inhibits RAD51)_HT115_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AREG | amphiregulin |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| BAG2 | BCL2-associated athanogene 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BIN1 | bridging integrator 1 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CFD | complement factor D (adipsin) |
| CLU | clusterin |
| CREM | cAMP responsive element modulator |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTTN | cortactin |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP5 | dual specificity phosphatase 5 |
| EREG | epiregulin |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| G0S2 | G0/G1 switch 2 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HLA-B | major histocompatibility complex, class I, B |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| IDE | insulin-degrading enzyme |
| IER3 | immediate early response 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KYNU | kynureninase |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MBP | myelin basic protein |
| MMD | monocyte to macrophage differentiation-associated |
| MT1F | metallothionein 1F |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MXRA7 | matrix-remodelling associated 7 |
| NPY1R | neuropeptide Y receptor Y1 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| ODC1 | ornithine decarboxylase 1 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAC8 | placenta-specific 8 |
| PRNP | prion protein |
| RBP4 | retinol binding protein 4, plasma |
| REG3A | regenerating islet-derived 3 alpha |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SRPX | sushi-repeat containing protein, X-linked |
| TFF1 | trefoil factor 1 |
| TGFA | transforming growth factor, alpha |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TRIM16 | tripartite motif containing 16 |
| TSPO | translocator protein (18kDa) |
| TUBB2A | tubulin, beta 2A class IIa |
| TXNRD1 | thioredoxin reductase 1 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ANOS1 | anosmin 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CA1 | carbonic anhydrase I |
| CA12 | carbonic anhydrase XII |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLEC7A | C-type lectin domain family 7, member A |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DMD | dystrophin |
| DPYD | dihydropyrimidine dehydrogenase |
| EIF5 | eukaryotic translation initiation factor 5 |
| FAR2 | fatty acyl CoA reductase 2 |
| FOLR1 | folate receptor 1 (adult) |
| HOPX | HOP homeobox |
| HOXB2 | homeobox B2 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| NARFL | nuclear prelamin A recognition factor-like |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NEFL | neurofilament, light polypeptide |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NPTX2 | neuronal pentraxin II |
| NSG1 | neuron specific gene family member 1 |
| OXA1L | oxidase (cytochrome c) assembly 1-like |
| PDGFC | platelet derived growth factor C |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POSTN | periostin, osteoblast specific factor |
| PRKCB | protein kinase C, beta |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| RGCC | regulator of cell cycle |
| RSRP1 | arginine/serine-rich protein 1 |
| RTN2 | reticulon 2 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SFTPD | surfactant protein D |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOSTDC1 | sclerostin domain containing 1 |
| SPEN | spen family transcriptional repressor |
| SULF1 | sulfatase 1 |
| TCF4 | transcription factor 4 |
| TFRC | transferrin receptor |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMSB15A | thymosin beta 15a |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNS1 | tensin 1 |
| TSPAN13 | tetraspanin 13 |
