BRD-K11558771_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K11558771_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLDN3 claudin 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
GCA grancalcin, EF-hand calcium binding protein
GLRX glutaredoxin (thioltransferase)
GPRC5A G protein-coupled receptor, class C, group 5, member A
HSPA1A heat shock 70kDa protein 1A
JMJD6 jumonji domain containing 6
LEF1 lymphoid enhancer-binding factor 1
MMD monocyte to macrophage differentiation-associated
MPZL1 myelin protein zero-like 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NRGN neurogranin (protein kinase C substrate, RC3)
PRKCZ protein kinase C, zeta
RAB2A RAB2A, member RAS oncogene family
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC46A3 solute carrier family 46, member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
BEX1 brain expressed, X-linked 1
CIRBP cold inducible RNA binding protein
COL3A1 collagen, type III, alpha 1
GRWD1 glutamate-rich WD repeat containing 1
GSAP gamma-secretase activating protein
IGFBP3 insulin-like growth factor binding protein 3
KEAP1 kelch-like ECH-associated protein 1
OBSL1 obscurin-like 1
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VTCN1 V-set domain containing T cell activation inhibitor 1