BRD-K11558771_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K11558771_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKAP12 A kinase (PRKA) anchor protein 12
BST2 bone marrow stromal cell antigen 2
C8ORF4 chromosome 8 open reading frame 4
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHPT1 choline phosphotransferase 1
CHRDL1 chordin-like 1
COL9A3 collagen, type IX, alpha 3
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
CPD carboxypeptidase D
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRLF1 cytokine receptor-like factor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EDNRA endothelin receptor type A
EIF5A eukaryotic translation initiation factor 5A
F3 coagulation factor III (thromboplastin, tissue factor)
FAM63A family with sequence similarity 63, member A
FCGBP Fc fragment of IgG binding protein
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXG1 forkhead box G1
FOXO4 forkhead box O4
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
HN1 hematological and neurological expressed 1
HSPA14 heat shock 70kDa protein 14
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRRC16A leucine rich repeat containing 16A
MSX1 msh homeobox 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MTMR11 myotubularin related protein 11
MVP major vault protein
MXRA7 matrix-remodelling associated 7
PAM peptidylglycine alpha-amidating monooxygenase
PEG10 paternally expressed 10
PFKP phosphofructokinase, platelet
PHYH phytanoyl-CoA 2-hydroxylase
PLAT plasminogen activator, tissue
PRKCA protein kinase C, alpha
PRSS8 protease, serine, 8
RABAC1 Rab acceptor 1 (prenylated)
RNF167 ring finger protein 167
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFN stratifin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SST somatostatin
STXBP1 syntaxin binding protein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMSB15A thymosin beta 15a
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AEBP1 AE binding protein 1
ATF5 activating transcription factor 5
AUTS2 autism susceptibility candidate 2
BGN biglycan
BPTF bromodomain PHD finger transcription factor
C5AR1 complement component 5a receptor 1
CADM1 cell adhesion molecule 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
DENND2D DENN/MADD domain containing 2D
EREG epiregulin
FAM20B family with sequence similarity 20, member B
GATAD1 GATA zinc finger domain containing 1
GPNMB glycoprotein (transmembrane) nmb
GTPBP8 GTP-binding protein 8 (putative)
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KEAP1 kelch-like ECH-associated protein 1
LOXL1 lysyl oxidase-like 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
PDLIM5 PDZ and LIM domain 5
PECAM1 platelet/endothelial cell adhesion molecule 1
PLCB4 phospholipase C, beta 4
PTGIS prostaglandin I2 (prostacyclin) synthase
SPAG7 sperm associated antigen 7
SULF1 sulfatase 1
THBS1 thrombospondin 1
VCAN versican
ZBTB20 zinc finger and BTB domain containing 20