Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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84 genes differentially expressed following the BRD-K11634954_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACSL3 | acyl-CoA synthetase long-chain family member 3 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ARMCX6 | armadillo repeat containing, X-linked 6 |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CFB | complement factor B |
CHMP4A | charged multivesicular body protein 4A |
CRISP3 | cysteine-rich secretory protein 3 |
DDIT4 | DNA-damage-inducible transcript 4 |
DHCR7 | 7-dehydrocholesterol reductase |
EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
FGG | fibrinogen gamma chain |
HBB | hemoglobin, beta |
HMG20B | high mobility group 20B |
HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
IRF4 | interferon regulatory factor 4 |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
LY75 | lymphocyte antigen 75 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
MAGED1 | melanoma antigen family D1 |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MLPH | melanophilin |
MSMO1 | methylsterol monooxygenase 1 |
NEFH | neurofilament, heavy polypeptide |
PLA1A | phospholipase A1 member A |
POSTN | periostin, osteoblast specific factor |
PRAME | preferentially expressed antigen in melanoma |
RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
RHOBTB3 | Rho-related BTB domain containing 3 |
RNASE4 | ribonuclease, RNase A family, 4 |
RRAGD | Ras-related GTP binding D |
SC5D | sterol-C5-desaturase |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SQLE | squalene epoxidase |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
TRIB3 | tribbles pseudokinase 3 |
VTCN1 | V-set domain containing T cell activation inhibitor 1 |
WFS1 | Wolfram syndrome 1 (wolframin) |
Symbol | Name |
---|---|
ADIRF | adipogenesis regulatory factor |
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
BSG | basigin (Ok blood group) |
C6ORF62 | chromosome 6 open reading frame 62 |
CD44 | CD44 molecule (Indian blood group) |
CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
CTSC | cathepsin C |
CYR61 | cysteine-rich, angiogenic inducer, 61 |
DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
ENO1 | enolase 1, (alpha) |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FBN2 | fibrillin 2 |
FGFBP1 | fibroblast growth factor binding protein 1 |
FHL1 | four and a half LIM domains 1 |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
GEM | GTP binding protein overexpressed in skeletal muscle |
HTRA1 | HtrA serine peptidase 1 |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
KLF6 | Kruppel-like factor 6 |
MAT2A | methionine adenosyltransferase II, alpha |
MCL1 | myeloid cell leukemia 1 |
MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
NFIB | nuclear factor I/B |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
SDC4 | syndecan 4 |
SHB | Src homology 2 domain containing adaptor protein B |
SIK1 | salt-inducible kinase 1 |
SOX4 | SRY (sex determining region Y)-box 4 |
SRSF5 | serine/arginine-rich splicing factor 5 |
TAGLN2 | transgelin 2 |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
THBS1 | thrombospondin 1 |
VAMP3 | vesicle-associated membrane protein 3 |
WWTR1 | WW domain containing transcription regulator 1 |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
ZFAND5 | zinc finger, AN1-type domain 5 |
ZNF586 | zinc finger protein 586 |