BRD-K12057390_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K12057390_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARF3 ADP-ribosylation factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPHL biphenyl hydrolase-like (serine hydrolase)
C3 complement component 3
CEP57 centrosomal protein 57kDa
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CDC42 cell division cycle 42
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CTGF connective tissue growth factor
DHRS2 dehydrogenase/reductase (SDR family) member 2
FAIM Fas apoptotic inhibitory molecule
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IGFBP3 insulin-like growth factor binding protein 3
KLF6 Kruppel-like factor 6
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2