| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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108 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASS1 | argininosuccinate synthase 1 |
| ATF3 | activating transcription factor 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CENPE | centromere protein E, 312kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CYTH1 | cytohesin 1 |
| DST | dystonin |
| FOXO1 | forkhead box O1 |
| FZD7 | frizzled class receptor 7 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA3 | GATA binding protein 3 |
| GPX3 | glutathione peroxidase 3 |
| HBP1 | HMG-box transcription factor 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HMOX1 | heme oxygenase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL15 | interleukin 15 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa |
| KIF14 | kinesin family member 14 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL21 | kelch-like family member 21 |
| LPL | lipoprotein lipase |
| MME | membrane metallo-endopeptidase |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCB4 | phospholipase C, beta 4 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPL | periplakin |
| PTK2 | protein tyrosine kinase 2 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS2 | regulator of G-protein signaling 2 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC35F2 | solute carrier family 35, member F2 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| STOM | stomatin |
| STX1A | syntaxin 1A (brain) |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| TXNIP | thioredoxin interacting protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| BAG2 | BCL2-associated athanogene 2 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| CCND1 | cyclin D1 |
| CD83 | CD83 molecule |
| CDC25A | cell division cycle 25A |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EMX2 | empty spiracles homeobox 2 |
| EREG | epiregulin |
| EXOSC4 | exosome component 4 |
| FASTKD5 | FAST kinase domains 5 |
| FEN1 | flap structure-specific endonuclease 1 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOSL1 | FOS-like antigen 1 |
| GLIPR1 | GLI pathogenesis-related 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPA14 | heat shock 70kDa protein 14 |
| HSPA1A | heat shock 70kDa protein 1A |
| IL1B | interleukin 1, beta |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| KRT18 | keratin 18, type I |
| LOC100505650 | uncharacterized LOC100505650 |
| LPXN | leupaxin |
| LTF | lactotransferrin |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAT2A | methionine adenosyltransferase II, alpha |
| MEIS1 | Meis homeobox 1 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MXRA7 | matrix-remodelling associated 7 |
| NAV3 | neuron navigator 3 |
| NUP62 | nucleoporin 62kDa |
| PEG3 | paternally expressed 3 |
| PODXL | podocalyxin-like |
| PPIF | peptidylprolyl isomerase F |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| RAD51C | RAD51 paralog C |
| RGS4 | regulator of G-protein signaling 4 |
| RPIA | ribose 5-phosphate isomerase A |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCG5 | secretogranin V |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SQLE | squalene epoxidase |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TLR4 | toll-like receptor 4 |
