| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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84 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATF3 | activating transcription factor 3 |
| BLNK | B-cell linker |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLC | Charcot-Leyden crystal galectin |
| CYTH1 | cytohesin 1 |
| FOXN3 | forkhead box N3 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| HBP1 | HMG-box transcription factor 1 |
| IDS | iduronate 2-sulfatase |
| IGF1R | insulin-like growth factor 1 receptor |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| KIF14 | kinesin family member 14 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL21 | kelch-like family member 21 |
| LAGE3 | L antigen family, member 3 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MGLL | monoglyceride lipase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PTK2 | protein tyrosine kinase 2 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLE4 | transducin-like enhancer of split 4 |
| TMSB15A | thymosin beta 15a |
| TSC22D3 | TSC22 domain family, member 3 |
| TUBA1A | tubulin, alpha 1a |
| TUBB2A | tubulin, beta 2A class IIa |
| VNN1 | vanin 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACTN1 | actinin, alpha 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| BAG2 | BCL2-associated athanogene 2 |
| CA12 | carbonic anhydrase XII |
| CCND1 | cyclin D1 |
| CDC25A | cell division cycle 25A |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CLU | clusterin |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| EXOSC4 | exosome component 4 |
| FASTKD5 | FAST kinase domains 5 |
| HES1 | hes family bHLH transcription factor 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| KLK10 | kallikrein-related peptidase 10 |
| LOC100505650 | uncharacterized LOC100505650 |
| LTF | lactotransferrin |
| MAT2A | methionine adenosyltransferase II, alpha |
| MMP7 | matrix metallopeptidase 7 |
| MYLK | myosin light chain kinase |
| PALLD | palladin, cytoskeletal associated protein |
| PCP4 | Purkinje cell protein 4 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PON2 | paraoxonase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAME | preferentially expressed antigen in melanoma |
| RAD51C | RAD51 paralog C |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RPL39L | ribosomal protein L39-like |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100A8 | S100 calcium binding protein A8 |
| SCG5 | secretogranin V |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SFRP4 | secreted frizzled-related protein 4 |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
| SPAG4 | sperm associated antigen 4 |
| SPP1 | secreted phosphoprotein 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WT1 | Wilms tumor 1 |
