| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
110 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ANXA1 | annexin A1 |
| ANXA4 | annexin A4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CGA | glycoprotein hormones, alpha polypeptide |
| COL18A1 | collagen, type XVIII, alpha 1 |
| CRISP3 | cysteine-rich secretory protein 3 |
| CTSA | cathepsin A |
| CTSH | cathepsin H |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| EIF5A | eukaryotic translation initiation factor 5A |
| FOXO4 | forkhead box O4 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPX4 | glutathione peroxidase 4 |
| GRN | granulin |
| ICAM1 | intercellular adhesion molecule 1 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 |
| IGF2R | insulin-like growth factor 2 receptor |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KRT19 | keratin 19, type I |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B |
| MGLL | monoglyceride lipase |
| MLPH | melanophilin |
| MMP1 | matrix metallopeptidase 1 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXTR | oxytocin receptor |
| PDGFC | platelet derived growth factor C |
| PROS1 | protein S (alpha) |
| PRSS8 | protease, serine, 8 |
| RAP1GAP | RAP1 GTPase activating protein |
| S100P | S100 calcium binding protein P |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC22A18 | solute carrier family 22, member 18 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| SQSTM1 | sequestosome 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TPP1 | tripeptidyl peptidase I |
| TRAPPC6A | trafficking protein particle complex 6A |
| VAT1 | vesicle amine transport 1 |
| Symbol | Name |
|---|---|
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| ASPN | asporin |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCND2 | cyclin D2 |
| CDC20 | cell division cycle 20 |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CDC7 | cell division cycle 7 |
| CENPU | centromere protein U |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| H2AFX | H2A histone family, member X |
| H2AFZ | H2A histone family, member Z |
| HMGB1 | high mobility group box 1 |
| HMGB2 | high mobility group box 2 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) |
| LMNB1 | lamin B1 |
| MCAM | melanoma cell adhesion molecule |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MELK | maternal embryonic leucine zipper kinase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| MYCBP | MYC binding protein |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NELL2 | NEL-like 2 (chicken) |
| PARP2 | poly (ADP-ribose) polymerase 2 |
| PCNA | proliferating cell nuclear antigen |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKRIR | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
| RANBP1 | RAN binding protein 1 |
| REEP1 | receptor accessory protein 1 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TK1 | thymidine kinase 1, soluble |
| TMPO | thymopoietin |
| TUBG1 | tubulin, gamma 1 |
| VRK1 | vaccinia related kinase 1 |
| ZWINT | ZW10 interacting kinetochore protein |
