| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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78 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHNAK2 | AHNAK nucleoprotein 2 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ANOS1 | anosmin 1 |
| ANXA1 | annexin A1 |
| ANXA4 | annexin A4 |
| BEX4 | brain expressed, X-linked 4 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CFD | complement factor D (adipsin) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| COLEC12 | collectin sub-family member 12 |
| EPCAM | epithelial cell adhesion molecule |
| F11R | F11 receptor |
| FAM107A | family with sequence similarity 107, member A |
| FTH1 | ferritin, heavy polypeptide 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GRN | granulin |
| HBP1 | HMG-box transcription factor 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HMG20B | high mobility group 20B |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| KRT18 | keratin 18, type I |
| KRT19 | keratin 19, type I |
| KRT8 | keratin 8, type II |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAGEA12 | melanoma antigen family A12 |
| MUC16 | mucin 16, cell surface associated |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RAB31 | RAB31, member RAS oncogene family |
| RGS10 | regulator of G-protein signaling 10 |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC38A1 | solute carrier family 38, member 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| SQSTM1 | sequestosome 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| TCTA | T-cell leukemia translocation altered |
| TMEM30B | transmembrane protein 30B |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPD52 | tumor protein D52 |
| TPP1 | tripeptidyl peptidase I |
| VAT1 | vesicle amine transport 1 |
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADM | adrenomedullin |
| AQP3 | aquaporin 3 (Gill blood group) |
| BARD1 | BRCA1 associated RING domain 1 |
| CCND2 | cyclin D2 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDC45 | cell division cycle 45 |
| CDC6 | cell division cycle 6 |
| CENPU | centromere protein U |
| CTPS1 | CTP synthase 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DONSON | downstream neighbor of SON |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FEN1 | flap structure-specific endonuclease 1 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| ICMT | isoprenylcysteine carboxyl methyltransferase |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM6 | minichromosome maintenance complex component 6 |
| MELK | maternal embryonic leucine zipper kinase |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| PCNA | proliferating cell nuclear antigen |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGAM1 | phosphoglycerate mutase 1 (brain) |
| RFC2 | replication factor C (activator 1) 2, 40kDa |
| RRM2 | ribonucleotide reductase M2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SHCBP1 | SHC SH2-domain binding protein 1 |
