| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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65 genes differentially expressed following the BRD-K12184916_NVP-BEZ235_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADD3 | adducin 3 (gamma) |
| AGTR1 | angiotensin II receptor, type 1 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASPN | asporin |
| AURKA | aurora kinase A |
| AUTS2 | autism susceptibility candidate 2 |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CDC42 | cell division cycle 42 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CPE | carboxypeptidase E |
| FBN2 | fibrillin 2 |
| FST | follistatin |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| KIAA0355 | KIAA0355 |
| KRT23 | keratin 23, type I |
| LRRC15 | leucine rich repeat containing 15 |
| LYZ | lysozyme |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MBP | myelin basic protein |
| NID2 | nidogen 2 (osteonidogen) |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PEG10 | paternally expressed 10 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTN | pleiotrophin |
| RGS5 | regulator of G-protein signaling 5 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TSC22D3 | TSC22 domain family, member 3 |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| Symbol | Name |
|---|---|
| ACOT7 | acyl-CoA thioesterase 7 |
| ACTN1 | actinin, alpha 1 |
| ADIRF | adipogenesis regulatory factor |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| CHI3L2 | chitinase 3-like 2 |
| CLTB | clathrin, light chain B |
| COL1A1 | collagen, type I, alpha 1 |
| DENND2D | DENN/MADD domain containing 2D |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EXOSC4 | exosome component 4 |
| FLNA | filamin A, alpha |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| HOXC6 | homeobox C6 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| MAL | mal, T-cell differentiation protein |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PRDX2 | peroxiredoxin 2 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| QPCT | glutaminyl-peptide cyclotransferase |
| RRP1B | ribosomal RNA processing 1B |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TRIB2 | tribbles pseudokinase 2 |
