| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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62 genes differentially expressed following the BRD-K12343256_trametinib_HA1E_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALB | albumin |
| APOC1 | apolipoprotein C-I |
| AQP1 | aquaporin 1 (Colton blood group) |
| AUTS2 | autism susceptibility candidate 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| AZU1 | azurocidin 1 |
| CA2 | carbonic anhydrase II |
| CBS | cystathionine-beta-synthase |
| DDIT4 | DNA-damage-inducible transcript 4 |
| FAM129A | family with sequence similarity 129, member A |
| FHL1 | four and a half LIM domains 1 |
| FRY | furry homolog (Drosophila) |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLUL | glutamate-ammonia ligase |
| INSR | insulin receptor |
| MAPT | microtubule-associated protein tau |
| MPO | myeloperoxidase |
| MXRA5 | matrix-remodelling associated 5 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCDH17 | protocadherin 17 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PPL | periplakin |
| PRTN3 | proteinase 3 |
| RAP1GAP | RAP1 GTPase activating protein |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| STC2 | stanniocalcin 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMOD1 | tropomodulin 1 |
| VSNL1 | visinin-like 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| Symbol | Name |
|---|---|
| ANXA5 | annexin A5 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ATG3 | autophagy related 3 |
| AXL | AXL receptor tyrosine kinase |
| CNN3 | calponin 3, acidic |
| CRISP3 | cysteine-rich secretory protein 3 |
| CTSZ | cathepsin Z |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EFHD2 | EF-hand domain family, member D2 |
| FOSL1 | FOS-like antigen 1 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPX1 | glutathione peroxidase 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HSPA8 | heat shock 70kDa protein 8 |
| ITGB5 | integrin, beta 5 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) |
| NPTX2 | neuronal pentraxin II |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLAT | plasminogen activator, tissue |
| SDC2 | syndecan 2 |
| SRGN | serglycin |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TSPAN4 | tetraspanin 4 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
