Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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74 genes differentially expressed following the BRD-K12502280_TG-101348_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AKR1C3 | aldo-keto reductase family 1, member C3 |
APOD | apolipoprotein D |
AQP3 | aquaporin 3 (Gill blood group) |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
DAPK1 | death-associated protein kinase 1 |
DDIT4 | DNA-damage-inducible transcript 4 |
ENO2 | enolase 2 (gamma, neuronal) |
FNDC3B | fibronectin type III domain containing 3B |
FOLR1 | folate receptor 1 (adult) |
H1F0 | H1 histone family, member 0 |
HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
HIST1H2AC | histone cluster 1, H2ac |
HIST2H2BE | histone cluster 2, H2be |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
IFITM1 | interferon induced transmembrane protein 1 |
ITGAV | integrin, alpha V |
KIAA0226L | KIAA0226-like |
ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
MTSS1 | metastasis suppressor 1 |
NCAM1 | neural cell adhesion molecule 1 |
NRGN | neurogranin (protein kinase C substrate, RC3) |
NRIP1 | nuclear receptor interacting protein 1 |
PHGDH | phosphoglycerate dehydrogenase |
PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
PSAT1 | phosphoserine aminotransferase 1 |
PYGL | phosphorylase, glycogen, liver |
RHOBTB3 | Rho-related BTB domain containing 3 |
SSFA2 | sperm specific antigen 2 |
STXBP1 | syntaxin binding protein 1 |
SYBU | syntabulin (syntaxin-interacting) |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TMSB15A | thymosin beta 15a |
TSPAN3 | tetraspanin 3 |
VEGFA | vascular endothelial growth factor A |
Symbol | Name |
---|---|
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
BHLHE41 | basic helix-loop-helix family, member e41 |
C2CD5 | C2 calcium-dependent domain containing 5 |
C7 | complement component 7 |
CCL2 | chemokine (C-C motif) ligand 2 |
CDC25A | cell division cycle 25A |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
CDK4 | cyclin-dependent kinase 4 |
CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
COL10A1 | collagen, type X, alpha 1 |
CXCR4 | chemokine (C-X-C motif) receptor 4 |
DCN | decorin |
FABP4 | fatty acid binding protein 4, adipocyte |
FAS | Fas cell surface death receptor |
GBP2 | guanylate binding protein 2, interferon-inducible |
HSPB1 | heat shock 27kDa protein 1 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
KCTD12 | potassium channel tetramerization domain containing 12 |
KRT19 | keratin 19, type I |
KRT7 | keratin 7, type II |
MAGEA3 | melanoma antigen family A3 |
MCTP1 | multiple C2 domains, transmembrane 1 |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PLAC8 | placenta-specific 8 |
RGS5 | regulator of G-protein signaling 5 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
SFN | stratifin |
SORBS3 | sorbin and SH3 domain containing 3 |
SOX4 | SRY (sex determining region Y)-box 4 |
SPINK1 | serine peptidase inhibitor, Kazal type 1 |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TFF1 | trefoil factor 1 |
TLR4 | toll-like receptor 4 |
TMEM97 | transmembrane protein 97 |
TSPAN8 | tetraspanin 8 |
VCAM1 | vascular cell adhesion molecule 1 |