BRD-K12539581_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K12539581_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DSP desmoplakin
EIF4A1 eukaryotic translation initiation factor 4A1
FGF13 fibroblast growth factor 13
FGL2 fibrinogen-like 2
GEM GTP binding protein overexpressed in skeletal muscle
GREM1 gremlin 1, DAN family BMP antagonist
MAN1A1 mannosidase, alpha, class 1A, member 1
MSMB microseminoprotein, beta-
PPAP2B phosphatidic acid phosphatase type 2B
PPOX protoporphyrinogen oxidase
RCAN2 regulator of calcineurin 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS5 regulator of G-protein signaling 5
RND3 Rho family GTPase 3
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPRSS3 transmembrane protease, serine 3
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3

decreased expression

Symbol Name
CST3 cystatin C
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
GADD45B growth arrest and DNA-damage-inducible, beta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
PLAC8 placenta-specific 8
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
SPP1 secreted phosphoprotein 1
TSPAN13 tetraspanin 13