| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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101 genes differentially expressed following the BRD-K12787259_CX-5461_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDOA | aldolase A, fructose-bisphosphate |
| BAG2 | BCL2-associated athanogene 2 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CAPN6 | calpain 6 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| COL4A5 | collagen, type IV, alpha 5 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DFNA5 | deafness, autosomal dominant 5 |
| DUSP6 | dual specificity phosphatase 6 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOXO1 | forkhead box O1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| ICAM2 | intercellular adhesion molecule 2 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| KYNU | kynureninase |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LDHB | lactate dehydrogenase B |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MIR22HG | MIR22 host gene |
| MSX1 | msh homeobox 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PON2 | paraoxonase 2 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RPS27L | ribosomal protein S27-like |
| S100A11 | S100 calcium binding protein A11 |
| S100P | S100 calcium binding protein P |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| STC1 | stanniocalcin 1 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| VDAC1 | voltage-dependent anion channel 1 |
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AUTS2 | autism susceptibility candidate 2 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| CD1E | CD1e molecule |
| CD2 | CD2 molecule |
| CD8A | CD8a molecule |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DICER1 | dicer 1, ribonuclease type III |
| DPYD | dihydropyrimidine dehydrogenase |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FASTKD3 | FAST kinase domains 3 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| HBB | hemoglobin, beta |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGHM | immunoglobulin heavy constant mu |
| IGL | immunoglobulin lambda locus |
| IPO13 | importin 13 |
| ISL1 | ISL LIM homeobox 1 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| MARCH6 | membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase |
| MMP2 | matrix metallopeptidase 2 |
| MSH6 | mutS homolog 6 |
| MYO1B | myosin IB |
| NKX3-1 | NK3 homeobox 1 |
| PAPD7 | PAP associated domain containing 7 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PRKD3 | protein kinase D3 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPON1 | spondin 1, extracellular matrix protein |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| TCF4 | transcription factor 4 |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TMPO | thymopoietin |
| TPSAB1 | tryptase alpha/beta 1 |
