Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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134 genes differentially expressed following the BRD-K12867552_THM-I-94_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABAT | 4-aminobutyrate aminotransferase |
ALDOC | aldolase C, fructose-bisphosphate |
AQP1 | aquaporin 1 (Colton blood group) |
AREG | amphiregulin |
ATF3 | activating transcription factor 3 |
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
BTG2 | BTG family, member 2 |
CA2 | carbonic anhydrase II |
CADM1 | cell adhesion molecule 1 |
CALR | calreticulin |
CD24 | CD24 molecule |
CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
CFD | complement factor D (adipsin) |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CREM | cAMP responsive element modulator |
DLK1 | delta-like 1 homolog (Drosophila) |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EMP1 | epithelial membrane protein 1 |
EZR | ezrin |
FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
FOXF1 | forkhead box F1 |
GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
GSTM3 | glutathione S-transferase mu 3 (brain) |
HSPA2 | heat shock 70kDa protein 2 |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
IFI27 | interferon, alpha-inducible protein 27 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL32 | interleukin 32 |
INSIG1 | insulin induced gene 1 |
MAGEA3 | melanoma antigen family A3 |
MAGEA6 | melanoma antigen family A6 |
METRN | meteorin, glial cell differentiation regulator |
MGP | matrix Gla protein |
MLF1 | myeloid leukemia factor 1 |
MMD | monocyte to macrophage differentiation-associated |
MT1X | metallothionein 1X |
NOSIP | nitric oxide synthase interacting protein |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
OSBPL3 | oxysterol binding protein-like 3 |
PDE4B | phosphodiesterase 4B, cAMP-specific |
PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
PLAT | plasminogen activator, tissue |
PLAU | plasminogen activator, urokinase |
PNP | purine nucleoside phosphorylase |
PROM1 | prominin 1 |
PRSS21 | protease, serine, 21 (testisin) |
RAD9A | RAD9 homolog A (S. pombe) |
RBP1 | retinol binding protein 1, cellular |
RGCC | regulator of cell cycle |
RGS16 | regulator of G-protein signaling 16 |
RGS2 | regulator of G-protein signaling 2 |
SGK1 | serum/glucocorticoid regulated kinase 1 |
SOD2 | superoxide dismutase 2, mitochondrial |
SOX4 | SRY (sex determining region Y)-box 4 |
SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
SST | somatostatin |
STC1 | stanniocalcin 1 |
STK17A | serine/threonine kinase 17a |
STX1A | syntaxin 1A (brain) |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
ZFP36 | ZFP36 ring finger protein |
ZFP36L1 | ZFP36 ring finger protein-like 1 |
Symbol | Name |
---|---|
ALCAM | activated leukocyte cell adhesion molecule |
ANKRD10 | ankyrin repeat domain 10 |
ATF5 | activating transcription factor 5 |
BASP1 | brain abundant, membrane attached signal protein 1 |
C2CD5 | C2 calcium-dependent domain containing 5 |
CBR3 | carbonyl reductase 3 |
CCNA2 | cyclin A2 |
CCND1 | cyclin D1 |
CDC20 | cell division cycle 20 |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CDK4 | cyclin-dependent kinase 4 |
CKAP4 | cytoskeleton-associated protein 4 |
CSK | c-src tyrosine kinase |
CTSL | cathepsin L |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
FAM57A | family with sequence similarity 57, member A |
FXYD3 | FXYD domain containing ion transport regulator 3 |
GAS1 | growth arrest-specific 1 |
GAS2 | growth arrest-specific 2 |
GSPT2 | G1 to S phase transition 2 |
HOXB7 | homeobox B7 |
HOXC6 | homeobox C6 |
IGF1R | insulin-like growth factor 1 receptor |
IGFBP3 | insulin-like growth factor binding protein 3 |
IRS2 | insulin receptor substrate 2 |
ITGB5 | integrin, beta 5 |
KIAA0368 | KIAA0368 |
KIF20A | kinesin family member 20A |
KLK2 | kallikrein-related peptidase 2 |
KLK3 | kallikrein-related peptidase 3 |
KPNB1 | karyopherin (importin) beta 1 |
KRT15 | keratin 15, type I |
MGST2 | microsomal glutathione S-transferase 2 |
MRPS2 | mitochondrial ribosomal protein S2 |
MSMB | microseminoprotein, beta- |
MYC | v-myc avian myelocytomatosis viral oncogene homolog |
NEFH | neurofilament, heavy polypeptide |
NOV | nephroblastoma overexpressed |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
NUP62 | nucleoporin 62kDa |
OBSL1 | obscurin-like 1 |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PLK1 | polo-like kinase 1 |
POSTN | periostin, osteoblast specific factor |
PUF60 | poly-U binding splicing factor 60KDa |
RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
RPL27A | ribosomal protein L27a |
RPS11 | ribosomal protein S11 |
SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SORD | sorbitol dehydrogenase |
SPDEF | SAM pointed domain containing ETS transcription factor |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
SPRY2 | sprouty homolog 2 (Drosophila) |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
TARP | TCR gamma alternate reading frame protein |
TLK1 | tousled-like kinase 1 |
TP53 | tumor protein p53 |
TPM1 | tropomyosin 1 (alpha) |
TSPAN8 | tetraspanin 8 |
UBE2C | ubiquitin-conjugating enzyme E2C |
USP22 | ubiquitin specific peptidase 22 |
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
VDAC1 | voltage-dependent anion channel 1 |
WARS | tryptophanyl-tRNA synthetase |
WDR43 | WD repeat domain 43 |
YBX3 | Y box binding protein 3 |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
ZMYM2 | zinc finger, MYM-type 2 |