| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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131 genes differentially expressed following the BRD-K13094524_PFI-1_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANXA3 | annexin A3 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
| ATF3 | activating transcription factor 3 |
| CALCA | calcitonin-related polypeptide alpha |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CCND2 | cyclin D2 |
| CD24 | CD24 molecule |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDK19 | cyclin-dependent kinase 19 |
| CKM | creatine kinase, muscle |
| CLGN | calmegin |
| CORO1A | coronin, actin binding protein, 1A |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DSP | desmoplakin |
| EFNB2 | ephrin-B2 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| EPHA3 | EPH receptor A3 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FZD5 | frizzled class receptor 5 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| H2BFS | H2B histone family, member S (pseudogene) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HTRA1 | HtrA serine peptidase 1 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IER5 | immediate early response 5 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LHFP | lipoma HMGIC fusion partner |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MEST | mesoderm specific transcript |
| METTL7A | methyltransferase like 7A |
| MID1 | midline 1 |
| MMP1 | matrix metallopeptidase 1 |
| MMP10 | matrix metallopeptidase 10 |
| MMP12 | matrix metallopeptidase 12 |
| MMP3 | matrix metallopeptidase 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NEB | nebulin |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ODC1 | ornithine decarboxylase 1 |
| PCDH9 | protocadherin 9 |
| PEG10 | paternally expressed 10 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SIK1 | salt-inducible kinase 1 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TFF1 | trefoil factor 1 |
| TMEM100 | transmembrane protein 100 |
| TNNC1 | troponin C type 1 (slow) |
| TSPAN8 | tetraspanin 8 |
| TTN | titin |
| TXNIP | thioredoxin interacting protein |
| TXNRD1 | thioredoxin reductase 1 |
| UBE3C | ubiquitin protein ligase E3C |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACTN1 | actinin, alpha 1 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| BST2 | bone marrow stromal cell antigen 2 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CD59 | CD59 molecule, complement regulatory protein |
| COL3A1 | collagen, type III, alpha 1 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| DCLK1 | doublecortin-like kinase 1 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EMP3 | epithelial membrane protein 3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| HOXB7 | homeobox B7 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HSPB1 | heat shock 27kDa protein 1 |
| IFITM3 | interferon induced transmembrane protein 3 |
| JADE2 | jade family PHD finger 2 |
| KIAA0907 | KIAA0907 |
| KRT17 | keratin 17, type I |
| KRT18 | keratin 18, type I |
| LAPTM4B | lysosomal protein transmembrane 4 beta |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| MCAM | melanoma cell adhesion molecule |
| MFAP2 | microfibrillar-associated protein 2 |
| MOK | MOK protein kinase |
| MT1E | metallothionein 1E |
| MXRA7 | matrix-remodelling associated 7 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| PKP4 | plakophilin 4 |
| PLIN2 | perilipin 2 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PON3 | paraoxonase 3 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RGS10 | regulator of G-protein signaling 10 |
| SCGB1D2 | secretoglobin, family 1D, member 2 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TLR4 | toll-like receptor 4 |
| UBXN8 | UBX domain protein 8 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
