BRD-K13094524_PFI-1_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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77 genes differentially expressed following the BRD-K13094524_PFI-1_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
ARG2 arginase 2
ASPN asporin
CCNA1 cyclin A1
CHGB chromogranin B
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CPNE1 copine I
CTGF connective tissue growth factor
CTSK cathepsin K
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DEFB1 defensin, beta 1
DUSP10 dual specificity phosphatase 10
EPHA3 EPH receptor A3
F13A1 coagulation factor XIII, A1 polypeptide
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GSN gelsolin
HDGFRP3 hepatoma-derived growth factor, related protein 3
HOOK2 hook microtubule-tethering protein 2
INSR insulin receptor
KIAA1033 KIAA1033
MMP11 matrix metallopeptidase 11
MXRA7 matrix-remodelling associated 7
NPIPB3 nuclear pore complex interacting protein family, member B3
NTS neurotensin
PIH1D1 PIH1 domain containing 1
PNMAL1 paraneoplastic Ma antigen family-like 1
PRAME preferentially expressed antigen in melanoma
PTGDS prostaglandin D2 synthase 21kDa (brain)
SCAND1 SCAN domain containing 1
SEPP1 selenoprotein P, plasma, 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFRP4 secreted frizzled-related protein 4
SNAI2 snail family zinc finger 2
SQSTM1 sequestosome 1
STXBP1 syntaxin binding protein 1
TCTN1 tectonic family member 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI2 tissue factor pathway inhibitor 2
TOX3 TOX high mobility group box family member 3
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ATG3 autophagy related 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC86 coiled-coil domain containing 86
CLC Charcot-Leyden crystal galectin
COL9A3 collagen, type IX, alpha 3
CREB1 cAMP responsive element binding protein 1
CYB5A cytochrome b5 type A (microsomal)
DEPTOR DEP domain containing MTOR-interacting protein
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
GLUL glutamate-ammonia ligase
HCAR3 hydroxycarboxylic acid receptor 3
IL6ST interleukin 6 signal transducer
KLF4 Kruppel-like factor 4 (gut)
MAOA monoamine oxidase A
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PTPRK protein tyrosine phosphatase, receptor type, K
PXMP2 peroxisomal membrane protein 2, 22kDa
RAD23B RAD23 homolog B (S. cerevisiae)
RGS2 regulator of G-protein signaling 2
SELENBP1 selenium binding protein 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SORBS2 sorbin and SH3 domain containing 2
SPRED2 sprouty-related, EVH1 domain containing 2
SYBU syntabulin (syntaxin-interacting)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
VEGFA vascular endothelial growth factor A